Registry-based systematic review maps non-pharmacological cancer trials in Africa
Are lifestyle changes for cancer in Africa being studied enough, or do we need more local trials?
This registry-based systematic review analyzed 53 trials of lifestyle and non-pharmacological interventions for cancer patients in Africa. I…
Advice from wealthy nations may not work in Africa, where most cancer lifestyle trials happen in Egypt while Kenya and Nigeria are largely i…
Reiki reduced pain and improved quality of life in hospitalized children with leukemia aged 5-7
Reiki Helps Kids With Leukemia Feel Less Pain
This double-blind randomized controlled trial of 66 hospitalized children with leukemia aged 5-7 years compared Reiki with pseudo-Reiki and …
A gentle hand on the forehead helped children aged five to seven with leukemia feel less pain and improve their quality of life during hospi…
Combining chemotherapy, immunotherapy, and high-dose radiation achieved remission in a patient with cervical esophageal adenocarcinoma.
Rare throat cancer vanishes after bold three-pronged treatment
This case report describes a 39-year-old male with cervical esophageal adenocarcinoma treated with standard chemotherapy and immunotherapy c…
A 39-year-old man with rare throat cancer reached complete remission after doctors combined chemo, immunotherapy, and high-dose radiation.
Systematic review of radionuclide theranostics in lung cancer patients
Smart Cancer Tracker Finds Lung Tumors and Fights Back
This systematic review evaluated radionuclide theranostics for patients with lung cancer. Specific study details, sample sizes, and primary …
Tiny radioactive 'smart bombs' can spot lung cancer cells on scans and then destroy them from the inside when other treatments fail.
Narrative review discusses dual role of senescent cells in cancer immunity and emerging therapeutic strategies.
Old Cells Can Fight Cancer
This narrative review examines the complex role of cellular senescence in cancer, specifically focusing on inducing senescence in tumor cell…
Old cells in your body can either kill tumors or help them grow, so new drugs aim to turn these zombie cells into powerful cancer fighters s…
Radiotherapy de-escalation strategies show reduced toxicity but modest clinical benefits in head and neck cancer cohorts.
Smarter Radiation for Head and Neck Cancer May Spare Patients Misery
This narrative review examines radiotherapy de-escalation strategies for head and neck squamous cell carcinoma and HPV-related oropharyngeal…
Doctors are testing gentler radiation plans that protect quality of life for people with throat, mouth, and neck cancers facing harsh side e…
Post-pancreatectomy chemotherapy linked to longer survival in pancreatic cancer, especially late-stage disease.
Chemo After Pancreatic Cancer Surgery: Who Truly Benefits?
A retrospective cohort study of 258 patients who underwent pancreatectomy for pancreatic cancer found that adjuvant chemotherapy was associa…
Chemo after pancreatic cancer surgery extends life for later-stage patients, but those with very early tumors may not see extra survival tim…
Multimodal AI applications in urologic oncology for prostate, bladder, and kidney cancers
Smarter Cancer Care: How AI Is Learning to See the Whole Picture
This narrative review examines multimodal artificial intelligence (AI) applications in urologic oncology for patients with prostate, bladder…
New AI tools combine scans, biopsies, and genes to give clearer answers for prostate, bladder, and kidney cancer patients, though most are s…
Izalontamab brengitecan shows activity in pretreated NSCLC with non-classical actionable genomic alterations
For lung cancer patients who have run out of options, a new drug mix shows promise but needs more time.
This phase 1 study evaluated izalontamab brengitecan (iza-bren) in 83 patients with locally advanced or metastatic NSCLC harboring actionabl…
Lung cancer patients with limited options saw tumors shrink in 40% of cases and disease controlled in 86% using a new drug mix with manageab…
Phase 1b ABBV-368 combinations in recurrent/metastatic HNSCC show 14.3% overall response rate
Early study of ABBV-368 plus other drugs showed limited tumor response in head and neck cancer patients.
This phase 1b, multicenter, open-label study enrolled 30 adults with recurrent or metastatic head and neck squamous cell carcinoma across th…
Early trials of ABBV-368 combined with other drugs showed limited tumor shrinkage in head and neck cancer patients despite a generally safe …
Aspirin and NSAIDs show little benefit for colorectal cancer prevention within 15 years but increase bleeding risk.
The Aspirin-Cancer Question Has a Complicated Answer
This Cochrane meta-analysis of randomized controlled trials involving 124,837 participants evaluated aspirin and nonsteroidal anti-inflammat…
A major new review finds that taking daily aspirin to prevent colon cancer offers little benefit for the first 15 years while increasing ble…
Ultrasound features like size ≥10 mm and vascularity associate with neoplastic gallbladder polyps in meta-analysis
These Ultrasound Clues Could Signal a Dangerous Gallbladder Polyp
A systematic review and meta-analysis of 30 observational studies including 8,953 patients with gallbladder polyps found that ultrasound ima…
Eight specific ultrasound signs can help doctors spot dangerous gallbladder polyps early, guiding patients who need surgery sooner.