Apalutamide plus ADT shows favorable survival trends in Asian and Japanese mCSPC patients
Asian Men See Real Benefit From New Prostate Drug
A Bayesian post hoc analysis of a phase 3 trial in Asian (n=221) and Japanese (n=51) patients with metastatic castration-sensitive prostate …
New analysis confirms the drug works well for Asian and Japanese patients, helping men with advanced prostate cancer live longer and delay p…
Complement inhibitors and FcRn blockers improve outcomes in AChR-Ab+ generalized myasthenia gravis
New Drugs Double Your Chance of Getting Better
A meta-analysis of 739 adults in RCTs and 588 in OLEs with acetylcholine receptor antibody-positive generalized myasthenia gravis found that…
New drugs for generalized myasthenia gravis double the odds of meaningful improvement while reducing the need for rescue therapy and severe …
Mepitel Film showed no difference versus StrataXRT for moist desquamation in breast cancer patients receiving adjuvant radiation therapy.
Does a new skin film really help radiation burns, or is it just a placebo?
This meta-analysis of randomized controlled trials evaluated Mepitel Film compared with StrataXRT in 120 breast cancer patients undergoing a…
A new skin film lowers severe radiation burn risk but nearly doubles the chance of itchy skin compared to another dressing option.
Pterional craniotomy resolves symptoms in pure intracavernous chondroma cases
Rare Brain Tumor Removed With New Surgical Trick
This case report with literature review describes surgical management of pure intracavernous chondromas in a 37-year-old male and seven prev…
A 37-year-old man regained clear vision after surgeons safely removed an exceptionally rare brain tumor from a dangerous skull area using a …
Intravenous vitamin C did not reduce gastrointestinal toxicities but attenuated platelet decline in nasopharyngeal carcinoma patients.
Intravenous vitamin C may help protect platelets during cancer treatment in Thailand
A randomized, double-blind, placebo-controlled trial in Thailand assessed 2 g of intravenous vitamin C prior to chemotherapy in patients wit…
Intravenous vitamin C helped slow platelet loss in Thai cancer patients undergoing treatment, though it did not reduce common side effects l…
Systematic review examines IL-5-targeted and multi-target therapies for eosinophil-associated diseases including asthma and COPD.
A Tricky Immune Messenger Behind Severe Asthma
This systematic review evaluated IL-5-targeted therapies, multi-target combination therapies, bispecific antibodies, and small-molecule inhi…
A protein called IL-5 fuels severe asthma, but new drugs targeting multiple immune pathways at once may finally help patients who haven't re…
Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
Local brain treatments linked to modest survival gains in rare head and neck cancer cases
This retrospective cohort analysis evaluated 201 patients with head and neck squamous cell carcinoma and brain metastasis from three tertiar…
Local brain treatments linked to lower death risk for rare head and neck cancer patients who develop brain metastases, though most still die…
Circulating protein signature predicts severe immune-related adverse events in relapsed/refractory lymphoma
Blood protein test may help predict severe side effects in lymphoma patients
A cohort study of 98 relapsed/refractory lymphoma patients at MD Anderson and Moffitt Cancer Centers found that a circulating protein signat…
A new blood test can spot lymphoma patients at high risk for severe immune reactions before dangerous side effects start.
Cell cycle pathway alterations linked to worse survival and recurrence after liver transplant for HCC
New Liver Test Uses DNA to Predict Survival
A prospective single-center cohort study of 91 patients with hepatocellular carcinoma (HCC) after liver transplant found that cell cycle pat…
A new liver test analyzes tumor DNA to predict survival, revealing that even small cancers can be dangerous if they carry specific genetic c…
Postoperative pain score and NACRT predict anastomotic leakage in rectal cancer patients after anterior resection
One Pain Score Could Save Your Stoma
A retrospective cohort study of 901 rectal cancer patients who underwent anterior resection found an overall anastomotic leakage incidence o…
A simple pain rating after surgery is the best early warning sign for a dangerous leak in the bowel connection.
TQB2618 plus penpulimab shows 52% response in PD-1 refractory Hodgkin lymphoma
A New Drug Duo Revives Hope for Hodgkin Lymphoma After Immunotherapy Fails
A phase Ib single-arm trial in 21 Chinese patients with PD-1/PD-L1 inhibitor-refractory classic Hodgkin lymphoma found TQB2618 plus penpulim…
A new two-drug combination revived hope for Hodgkin lymphoma patients who failed prior immunotherapy, achieving a 52% response rate in early…
Phase 1 trial of zamtocabtagene autoleucel shows 75% response in relapsed/refractory B-cell NHL
Can a new cell therapy help lymphoma patients who have run out of options?
A Phase 1 clinical trial in 12 patients with relapsed or refractory B-cell non-Hodgkin lymphoma evaluated zamtocabtagene autoleucel at two d…
Five of 12 lymphoma patients treated with a new cell therapy achieved complete remission with no cancer return after five years and no sever…