EHR-integrated symptom monitoring associates with reduced symptom prevalence and higher mortality risk in cancer patients
Chemo Side Effects Follow a Pattern — And It Could Save Lives
This secondary analysis of a cluster randomized clinical trial evaluated patients with gastrointestinal, thoracic, or gynecologic cancer ini…
Tracking fatigue, pain, and breathing trouble during chemotherapy helps predict which patients face the highest risk of death, allowing doct…
ML-driven decision aid reduces decisional conflict in prostate cancer screening discussions compared to standard education.
How AI Helps Older Men Decide on Prostate Cancer Tests
This randomized controlled trial evaluated a web-based, machine learning-driven decision aid versus video-based education in middle-aged and…
A new digital tool helps older men make clearer choices about prostate cancer tests by reducing their worry and confusion.
Systematic review finds age and Galassi type influence pediatric middle fossa arachnoid cyst outcomes
Younger Kids Need More Watchful Eyes for Brain Cysts
A systematic review and meta-analysis of 1,024 pediatric patients with middle fossa arachnoid cysts examined associations with age and Galas…
Younger children with brain cysts are more likely to need repeat surgeries and shunts, highlighting the need for age-specific monitoring.
Meta-analysis of 3,700 patients shows lobectomy and sub-lobar resection yield comparable overall survival for lung neuroendocrine tumors.
For This Rare Lung Cancer, Smaller Surgery May Work Just as Well
This systematic review and meta-analysis evaluated 3,700 patients with lung neuroendocrine tumors to compare lobectomy versus sub-lobar rese…
For rare lung neuroendocrine tumors, smaller surgeries like segmentectomy offer the same survival rates as removing an entire lung lobe.
Minimally invasive surgical thermal ablation shows improved technical success and safety in liver malignancy patients.
Minimally invasive surgery offers safe, effective treatment for liver cancer tumors
This systematic review and meta-analysis evaluated 3983 patients with hepatocellular carcinoma or colorectal liver metastases treated with m…
Minimally invasive surgery safely destroys liver cancer tumors with just 1% failure rate and 0.25% death risk for patients who can't have fu…
Simlukafusp alfa plus atezolizumab with or without bevacizumab shows antitumor activity in metastatic renal cell carcinoma
Does adding bevacizumab nearly triple the time before kidney cancer grows back?
A phase Ib randomized open-label study in 66 patients with metastatic renal cell carcinoma found objective response rates of 25% with simluk…
Adding bevacizumab nearly tripled the time before kidney cancer grew back compared to a two-drug mix in this early study.
In L858R-mutated NSCLC, ICI combinations improve progression-free survival versus chemotherapy in TKI-resistant patients.
Immune Drugs Work in This Lung Cancer, But Only as a Team
This systematic review and meta-analysis evaluated immune checkpoint inhibitor (ICI)-based treatments in EGFR L858R-mutated non-small cell l…
For lung cancer patients with a specific mutation, immune drugs alone fail but work when combined with other treatments to delay progression…
Physical activity improves fatigue and muscle strength in pediatric cancer patients based on a meta-analysis of 24 studies.
Does moving more help young cancer patients feel better and fight fatigue?
This systematic review and meta-analysis evaluated physical activity (PA) in children and adolescents with cancer across 24 studies. Signifi…
Getting moving helps young cancer patients feel less fatigued, build stronger muscles, and improve their ability to think clearly and connec…
Pyridostigmine improves symptoms and reduces costs in adults with AChR MG in a crossover trial.
The Pill Millions Take Daily Finally Gets Proof It Works
A randomized, double-blind, placebo-controlled crossover trial in 19 adults with anti-acetylcholine receptor-positive myasthenia gravis (ACh…
After decades of widespread use, a medication that helps people with myasthenia gravis regain muscle control now has its first rigorous clin…
Stereotactic body radiotherapy for painful spinal metastases showed high pain response rates in a single-arm phase II study.
Second Radiation Stops Spinal Pain Fast
This single-centre, single-arm phase II study evaluated re-irradiation stereotactic body radiotherapy (SBRT) in 34 patients with painful spi…
A second round of precise radiation safely stops severe spinal pain in most patients, offering new hope for those who previously had no opti…
Prehabilitation program improves physical and psychological outcomes in leukemia patients before chemotherapy
Getting Ready Before Chemotherapy Starts May Change How You Come Through It
A single-blind RCT of 86 newly diagnosed leukemia patients in China found a 12-week prehabilitation program integrating exercise, nutrition,…
Leukemia patients prepared with exercise and nutrition before chemotherapy walked farther and reported less anxiety and depression throughou…
Predictors of pathological upstaging in clinical stage T1 renal cell carcinoma include male gender, age, and irregular margins.
Could your kidney tumor look smaller than it really is inside?
This meta-analysis and systematic review evaluated 24,957 patients with clinical stage T1 renal cell carcinoma to identify predictors of pat…
A kidney tumor that looks small on a scan might actually be more advanced than doctors think, raising the risk of it returning after surgery…