Mitoxantrone liposome plus CMOP shows high response rates in untreated peripheral T-cell lymphoma patients.
New Drug Combo Helps Most Patients With Hard-to-Treat Lymphoma
This phase 1b multicenter clinical trial evaluated mitoxantrone hydrochloride liposome combined with cyclophosphamide, vincristine, and pred…
A new drug combo wrapped in fat bubbles helped 89% of patients with hard-to-treat lymphoma shrink tumors without causing deaths.
Phase 1/2 trial shows RT + bevacizumab + olaptesed pegol extends PFS and OS in unmethylated GBM
New Drug Combo Slows Brain Cancer Growth
A Phase 1/2 expansion arm in six patients with newly-diagnosed, unmethylated GBM found that adding bevacizumab to radiotherapy and olaptesed…
Adding a second drug to stop blood vessel growth gives patients with brain cancer more time before the disease returns.
Meta-analysis shows radiomics-based machine learning models predict recurrence risk in non-small cell lung cancer patients.
Your Lung Cancer Scan May Already Hold a Hidden Clue About Its Return
This systematic review and meta-analysis evaluated radiomics-based machine learning models for predicting recurrence risk in 7,964 patients …
Artificial intelligence can find hidden patterns in routine lung scans to predict if common lung cancer will return, giving patients a cruci…
MRLN sparing radiotherapy shows non-inferior survival, reduced toxicity in nasopharyngeal carcinoma
New Radiation Plan Saves Swallowing Power
A phase 3 RCT of 568 adults with untreated, non-metastatic nasopharyngeal carcinoma found MRLN sparing radiotherapy was non-inferior to stan…
A new radiation plan for throat cancer lets patients skip a specific area, helping them keep their swallowing strength and eat normally for …
Systematic review finds serum biomarkers show variable diagnostic accuracy for oral cancer detection
Blood Tests Could Spot Oral Cancer Sooner
A systematic review and meta-analysis of 3,309 subjects (2,069 with oral squamous cell carcinoma, 1,240 controls) examined multiple serum bi…
New blood tests using specific proteins could detect oral cancer before a visible lump forms, potentially saving lives through earlier diagn…
Serum triglyceride levels show no relationship with prostate cancer risk in a meta-analysis of Chinese men.
High Triglycerides Do Not Raise Prostate Cancer Risk in Chinese Men
This meta-analysis evaluated the association between serum triglyceride levels and prostate cancer risk among 4,732 Chinese men. The analysi…
High triglycerides do not increase prostate cancer risk in Chinese men, challenging earlier Western-based assumptions.
Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…
Predictive nomogram with spectral CT radiomics and deep learning features improves preoperative STAS prediction in surgically resected lung adenocarcinoma.
A Simple Scan May Now Predict a Hidden Lung Cancer Danger Before Surgery
This cohort study evaluated a predictive nomogram combining spectral dual-layer detector CT radiomics, deep learning features, and pleural i…
Doctors may soon use artificial intelligence to find a hidden sign of aggressive lung cancer before a patient ever goes into the operating r…
NSI-driven quality program linked to faster ambulation after liver resection for HCC
A Simple Hospital Checklist Is Helping Liver Cancer Patients Heal Faster
A cohort study of 172 patients undergoing curative liver resection for hepatocellular carcinoma compared a structured Nursing-Sensitive Indi…
Better teamwork and simple checklists after surgery are leading to safer, faster recoveries for liver cancer patients.
Dasatinib Added to Intensive Chemotherapy Fails to Improve Survival in CBF-AML
Adding Dasatinib to Chemo Does Not Help CBF-AML Patients
A phase 3 randomized trial in 202 adults with core-binding factor acute myeloid leukemia (CBF-AML) found adding dasatinib to intensive chemo…
Adding dasatinib to standard chemotherapy did not improve survival for adults with core-binding factor acute myeloid leukemia and increased …
Olaparib plus durvalumab showed activity in mCRPC patients previously treated with abiraterone or enzalutamide.
Two Cancer Drugs Teamed Up — Who Actually Benefits Most?
This single-arm, open-label phase 2 trial evaluated olaparib plus durvalumab in 60 men with metastatic castration-resistant prostate cancer …
A new prostate cancer drug combo helped men with specific DNA repair gene variants live more than twice as long without their cancer progres…
Meta-analysis finds immunotherapy efficacy in HCC varies by aetiology, strongest in HBV-related disease
1. HEADLINE
A systematic review and meta-analysis of 26 studies in hepatocellular carcinoma found immune checkpoint inhibitor efficacy varies by aetiolo…
For the first time, a major analysis confirms that *why* you have liver cancer is a powerful clue to *if* a leading treatment will help you …