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Oncology

864 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Tumor debulking plus chemotherapy did not improve overall survival in multiorgan metastatic colorectal cancer patients
Oncology RCT
Tumor debulking plus chemotherapy did not improve overall survival in multiorgan metastatic colorectal cancer patients Surgery Doesn’t Extend Life for Advanced Colon Cancer
This randomized clinical trial enrolled 382 adult patients with multiorgan metastatic colorectal cancer across 27 hospitals in the Netherlan…
This large study shows that removing tumors in advanced colon cancer doesn’t help people live longer.
Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors
Oncology RCT
Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors A Tiny Dose of This Cancer Drug Is Outperforming Chemo
This Phase III randomized trial evaluated ultra-low-dose nivolumab against standard chemotherapy in patients with advanced solid tumors prog…
Giving a much smaller dose of a powerful cancer drug can extend life with fewer side effects, making treatment more tolerable and accessible…
Pembrolizumab Plus Paclitaxel Improves Survival in Recurrent Ovarian Carcinoma Compared to Paclitaxel Alone
Oncology RCT
Pembrolizumab Plus Paclitaxel Improves Survival in Recurrent Ovarian Carcinoma Compared to Paclitaxel Alone New Drug Combo Extends Survival for Tough Ovarian Cancer
This randomised, double-blind phase 3 study evaluated pembrolizumab plus paclitaxel versus placebo plus paclitaxel in 643 female participant…
This new combination offers a meaningful survival boost for women with recurrent ovarian cancer that has become resistant to standard treatm…
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
Oncology RCT
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival Men with advanced prostate cancer may have fewer hot flashes with a new patch treatment
This phase 3 randomized trial evaluated 1360 men with locally advanced prostate cancer across 75 U.K.
A new patch for advanced prostate cancer showed similar cancer control to standard shots but caused fewer hot flashes in a large UK trial.
Meta-analysis finds mHealth reduces infections and PICC complications in pediatric cancer
Oncology Meta-analysis
Meta-analysis finds mHealth reduces infections and PICC complications in pediatric cancer Mobile Apps Cut Infection Risk for Children With Cancer
This systematic review and meta-analysis of 2645 pediatric cancer patients found that mHealth interventions significantly reduced infection …
Using phone apps helps children with cancer stay safer and feel better during treatment.
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
Oncology RCT
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer Combination therapy may help overcome resistance in esophageal cancer
This Phase 3 RCT in 55 patients with locally advanced esophageal squamous cell carcinoma compared neoadjuvant chemotherapy alone versus comb…
A small trial suggests combination therapy might help overcome resistance in esophageal cancer by targeting specific immune cells.
Nivolumab plus ipilimumab versus nivolumab in advanced neuroendocrine carcinoma phase II trial
Oncology RCT
Nivolumab plus ipilimumab versus nivolumab in advanced neuroendocrine carcinoma phase II trial New Combo Shows Modest Promise for Hard-to-Treat Neuroendocrine Cancers
This randomized phase II trial enrolled 185 patients with advanced neuroendocrine carcinoma refractory to platinum-based chemotherapy.
For patients with rare, aggressive neuroendocrine cancers that resist initial treatment, this study offers a new, though modest, combination…
Thunder-fire moxibustion may reduce fatigue in colorectal cancer patients undergoing chemotherapy
Oncology RCT
Thunder-fire moxibustion may reduce fatigue in colorectal cancer patients undergoing chemotherapy Cancer Fatigue Melts Away with Ancient Heat Therapy
This randomized controlled trial enrolled 77 patients with Qi stagnation and blood stasis type colorectal cancer undergoing chemotherapy.
It’s 3 p.m., and Li Wei feels like she’s hit a wall.
Review of immunotherapy innovations for triple-negative breast cancer survival
Oncology Sys. Review
Review of immunotherapy innovations for triple-negative breast cancer survival New Hope for Tough-to-Treat Breast Cancer
This narrative review examines immunotherapy innovations, including immune checkpoint inhibitors and combination strategies, for patients wi…
This approach may change how doctors treat one of the hardest forms of breast cancer.
Meta-analysis of real-world studies associates COVID-19 vaccination with improved survival in cancer patients on ICIs
Oncology Meta-analysis
Meta-analysis of real-world studies associates COVID-19 vaccination with improved survival in cancer patients on ICIs Cancer Patients Live Longer After COVID Shots
This meta-analysis of real-world studies evaluated 4,929 cancer patients receiving immune checkpoint inhibitors to assess COVID-19 vaccinati…
It started with a question doctors couldn’t answer: *Should patients on powerful cancer drugs get the COVID vaccine?* Some worried the immun…
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice
Oncology Sys. Review
Narrative review offers practical recommendations for implementing PET-guided therapy workflows in clinical practice PET scans now guide your radiation treatment
This narrative review synthesizes evidence regarding the implementation of PET-guided therapy workflows.
Imagine standing in a doctor's office waiting for radiation therapy.
Systematic review and meta-analysis of nurse-led shared decision-making for lung cancer screening uptake
Oncology Meta-analysis
Systematic review and meta-analysis of nurse-led shared decision-making for lung cancer screening uptake Nurse-led conversations may help high-risk lung cancer patients choose low-dose CT scans
This systematic review and meta-analysis evaluates nurse-led shared decision-making in high-risk lung cancer populations.
A review of 13,608 patients found nurse-led shared decision-making increased willingness to participate in lung cancer screening, with most …