Trastuzumab emtansine and trastuzumab deruxtecan use in three patients with ERBB2-amplified rare tumors
Rare tumors respond to targeted antibody drug treatments
This retrospective case series evaluated three patients with ERBB2-amplified rare tumors, including periampullary, salivary duct, and poorly…
Three patients with rare, aggressive cancers saw significant tumor shrinkage after receiving targeted antibody drug therapies.
Observational study identifies four immune subtypes in newly-diagnosed glioma grades 2-4 among 354 patients
New immune map shows how glioma types affect survival chances
This primary research article describes an observational study of 354 patients with newly-diagnosed glioma grades 2-4.
A new map of immune cells in brain tumors reveals four types that predict survival and guide future treatment choices for patients.
Review of observational data on non-sedated MRI feasibility in newly diagnosed ALL patients ages 3 to 10 years
Non-sedated MRI scans work for young leukemia patients with practice
This review synthesizes observational data from a community setting involving 17 newly diagnosed ALL patients and 30 controls ages 3 to 10 y…
Young children with acute lymphoblastic leukemia can undergo non-sedated MRI scans. Success rates improve with repeated visits and behaviora…
Network meta-analysis of pharmacological interventions for hand-foot syndrome in cancer patients undergoing chemotherapy
Simple cream could stop painful hand and foot syndrome side effects
This network meta-analysis evaluated pharmacological interventions for hand-foot syndrome prevention in cancer patients undergoing chemother…
New research suggests a common pain cream could protect cancer patients from painful hand and foot syndrome during treatment.
Mirtazapine and olanzapine reduce anxiety and depression scores in oral cavity cancer patients
Two Common Pills Ease Cancer Anxiety and Depression
This randomized controlled trial included 144 patients with oral cavity cancer.
Two well-known antidepressants significantly eased anxiety and depression in oral cancer patients, with mirtazapine showing a slight edge.
CPX-351 improves survival in AML with myelodysplasia-related changes
New leukemia treatment works best for specific gene type
This randomized phase 3 trial in 184 patients with AML and myelodysplasia-related mutations evaluated CPX-351 versus standard cytarabine plu…
A leukemia drug thought to help many patients actually works only in those with a specific genetic subtype, leaving others in need of better…
Meta-analysis of CD38-directed CAR-T therapy in relapsed refractory multiple myeloma reports high response rates
New CD38 CAR-T therapy shows high success rates for late-stage multiple myeloma patients
This systematic review and meta-analysis evaluated CD38-directed CAR-T cell therapy in patients with relapsed refractory multiple myeloma.
A new immune therapy targeting CD38 and BCMA offers deep remission for late-stage multiple myeloma patients while managing side effects like…
Narrative review evaluates urine-based PSMA detection technologies as emerging noninvasive diagnostics for prostate cancer
Urine Test for Prostate Cancer Could Cut Unnecessary Biopsies
This narrative review examines urine-based PSMA detection technologies, including antibody-based immunoassays and CRISPR/Cas12a-assisted sig…
A urine test that spots a prostate cancer protein may soon make screening safer and more accurate for millions of men.
Four daily mindful breathing sessions reduced ESAS scores in adult patients with advanced cancer compared to standard care alone
Four Daily Breathing Sessions Ease Cancer Symptoms Fast
This randomised controlled study enrolled 80 adult patients with advanced cancer who scored ≥4 in at least two symptoms on the Edmonton Symp…
Four daily mindful breathing sessions rapidly eased multiple symptoms for adults with advanced cancer in a small trial.
Protocol for randomized controlled trial of TEAS pretreatment for breast cancer-related lymphedema
New electrical therapy may stop breast cancer swelling before surgery starts
This document outlines a randomized controlled trial protocol evaluating transcutaneous electrical acupoint stimulation pretreatment in brea…
A new electrical therapy might stop arm swelling before breast cancer surgery begins
Memantine improved neuropathy severity and pain scores versus placebo in CIPN over eight weeks
Memantine eased nerve pain and tingling for chemotherapy patients in eight weeks
This randomized clinical trial enrolled 176 individuals with chemotherapy-induced peripheral neuropathy.
A new trial found memantine significantly reduced nerve pain and tingling in chemotherapy patients compared to placebo over eight weeks.
Autologous patch versus secondary intent healing for Mohs surgery wounds
This patch could speed healing after skin cancer surgery
This randomized controlled trial in 22 patients undergoing Mohs surgery compared an autologous patch to secondary intent healing.
After facial skin cancer surgery, wounds treated with a patch made from the patient’s blood healed with better moisture and less scarring th…