Receptor discordance in metastatic breast cancer lesions associated with poorer overall survival in a retrospective cohort study
When breast cancer changes its targets, does the current treatment still work?
This single-center retrospective cohort study analyzed 436 paired lesion samples from patients with primary and metastatic breast cancer.
Breast cancer often changes its targets, and when tumors lose the proteins doctors rely on, survival drops from 95 to 70 months depending on…
Residual disease after surgery linked to survival in low-grade serous ovarian cancer
For This Ovarian Cancer, Surgery Is Everything—Chemo May Not Help
This observational retrospective study of 25 patients with low-grade serous ovarian cancer found that residual disease status after primary …
For a rare ovarian cancer, a new study suggests that the quality of surgery is the single most important factor for survival, challenging th…
Retrospective review of 230 Northwest Ohio colorectal cancer patients identified demographic, lifestyle, and molecular risk factors
More Young Adults Are Getting Colon Cancer — Here’s What’s Behind It
This retrospective chart review examined 230 patients with colorectal cancer from the Northwest Ohio region to identify risk factors.
Colon cancer cases in adults aged 30 to 49 are rising fast, prompting new screening guidelines and a closer look at lifestyle risks in Ohio.
SinglePass Kronos device shows promise for liver biopsy tract closure in small series
New Device Stops Liver Biopsy Bleeding Before It Starts
This case report series evaluated the SinglePass Kronos electrocautery device for closing biopsy tracts in patients undergoing liver mass bi…
This simple new tool could make liver biopsies much safer by sealing the needle track instantly, reducing the need for long hospital stays.
Retrospective observational study evaluates systemic therapy surveillance in brain metastases patients
Observational study examines MRI surveillance patterns in patients with active brain metastases
This retrospective observational study abstract examines surveillance practices in 33 patients with active brain metastases treated with sys…
Doctors monitoring brain metastasis patients with new drugs found no difference in tumor growth or radiation needs whether they followed gui…
PM-TRPV4 positivity associated with invasive progression in patients with ductal carcinoma in situ
New Protein Test Predicts Which Breast Lesions Spread
This retrospective case-control study evaluated 44 patients with pure ductal carcinoma in situ (DCIS) to assess PM-TRPV4 status.
A new protein test on cell walls helps doctors predict which early breast changes might spread to invasive cancer.
Meta-analysis finds oral SERDs improve PFS over standard ET in HR+ HER2- ABC
New Drug Helps Some Breast Cancer Patients Live Longer
This systematic review and meta-analysis of 2,808 patients with HR+ HER2- advanced breast cancer found oral SERDs improved progression-free …
New oral pills help some advanced breast cancer patients live longer and fight back against drug resistance by blocking estrogen growth sign…
Systematic review and meta-analysis on incidental findings in trauma whole-body CT scans
Hidden Injuries Found in Trauma Scans
This systematic review and meta-analysis synthesized data on incidental findings from trauma whole-body CT scans.
Nearly 30% of trauma scans reveal hidden injuries needing treatment in adults, not children, requiring new safety rules for emergency rooms.
Online mindfulness-based cognitive therapy reduces distress in cancer patients over 9-month follow-up
Cancer Patients Find Lasting Calm With Simple Online Mindfulness
This secondary analysis of a randomized controlled trial evaluated online mindfulness-based cognitive therapy (eMBCT) in 161 cancer patients…
Simple online mindfulness tools offer lasting mental relief for cancer patients.
Narrative review offers qualitative synthesis without reported quantitative outcomes or safety data
Making Cancer Drugs Work Better: The New Roadmap Ahead
This source is a narrative review with no reported study population, sample size, or specific interventions.
Doctors are mapping four new ways to make immune cancer drugs work better for patients whose tumors hide from the body's defenses.
Review of STING agonists for high-grade and diffuse midline glioma discusses systemic toxicity and delivery constraints
New Brain Drug Target Could Wake Up the Immune System
This narrative review examines the potential of STING agonists, cyclic dinucleotides, and related compounds for treating high-grade glioma a…
A new brain drug target aims to wake up the immune system's defenses against dangerous, hard-to-treat tumors that hide from the body's natur…
Peer-led blended peer support program improves psychosocial adjustment in young- to middle-aged breast cancer patients
Can a peer support program help young breast cancer patients cope better after surgery?
In a single-center cluster RCT of 70 young- to middle-aged breast cancer patients, an 8-week peer-led, nurse-involved blended peer support p…
An 8-week peer support program helped young breast cancer patients feel more socially supported and face problems head-on after surgery.