Narrative review explores adipose tissue macrophage regulation for obesity and metabolic disorders
The Immune Cells Inside Fat Tissue That Drive Obesity's Hidden Damage
This narrative review examines targeted regulation of adipose tissue macrophages (ATMs) via mitochondrial, extracellular vesicle, probiotic,…
Specialized immune cells hiding inside your fat tissue are quietly driving the chronic inflammation that damages your heart, liver, and panc…
Case report and literature review on T-SMARCA4-DUT diagnosis and treatment response in a single patient
A Rare Tumor That Fooled Doctors at Every Step — Until One Test Changed Everything
This case report and literature review describes a 64-year-old male with thoracic SMARCA4-deficient undifferentiated tumor initially misdiag…
A rare chest tumor mimicking lung cancer was misdiagnosed until a specific genetic test revealed the true cause, proving one marker can prev…
Review compares 68Ga-pentixafor and 18F-FDG PET/CT in a single CLL patient
A New Scan Spots a Tricky Blood Cancer Far More Clearly
This case report and review of literature evaluates diagnostic performance of 68Ga-pentixafor versus 18F-FDG PET/CT in a 60-year-old woman w…
A new PET scan tracer spots chronic lymphocytic leukemia more clearly than standard imaging, helping doctors see disease extent in patients …
Narrative review assesses AI/ML adherence prediction in chronic disease patients globally with noted limitations
AI Can Now Predict Who Will Stop Taking Their Medication — Before They Do
This narrative review evaluates artificial intelligence and machine learning approaches for prospective adherence risk prediction in chronic…
AI tools can now predict which patients with chronic diseases like diabetes or HIV will stop taking their medication before it happens, allo…
Machine learning models predict survival in lymph-node-positive medullary thyroid carcinoma
A Machine Learning Tool Now Predicts Survival for One Tricky Thyroid Cancer
This cohort study evaluated machine learning models for predicting survival in patients with lymph-node-positive medullary thyroid carcinoma…
A new AI tool predicts survival for aggressive medullary thyroid cancer that has spread to lymph nodes, revealing that skipping surgery is t…
Colonic stents versus diverting stoma for malignant left-sided colorectal obstruction show similar long-term oncologic results
Two Paths Through a Blocked Colon — Which One Is Safer?
This single-center retrospective cohort study compared 24 patients treated with colonic stents to 32 patients who underwent a diverting stom…
For a blocked colon from cancer, a temporary stent works just as well as surgery to open the bowel, getting patients to treatment faster wit…
Liver cancer 5-year relative survival in Taizhou increased from 5.56% to 37.32% between 2004 and 2019-2023
Liver Cancer Survival in China Has Quietly Climbed — Here's Why
This retrospective cohort study analyzed 12,032 liver cancer patients diagnosed in Taizhou, eastern China, from 2004 to 2023.
Five-year liver cancer survival in eastern China nearly doubled over two decades, driven by earlier detection and better treatment access.
Immunoscore stratification shows prognostic value in HPV-associated oropharyngeal cancer
Your Immune System May Predict Throat Cancer Outcomes Better Than Doctors Thought
This international multicenter cohort study validated the Immunoscore (IS) in 191 patients with HPV-associated oropharyngeal squamous cell c…
A new immune scoring tool predicts survival better than standard staging for HPV-related throat cancer, potentially guiding gentler treatmen…
PRISM EHR-based model identifies adults at high risk for pancreatic ductal adenocarcinoma in real-world setting
Your Medical Records Might Flag Pancreatic Cancer Years Before Symptoms Appear
In a prospective multicenter cohort study of 6,282,123 adults, an EHR-based risk model identified individuals at high risk for pancreatic du…
An AI tool using routine health records can flag pancreatic cancer risk up to 3.5 years before symptoms appear in adults 40 and older.
Review describes Virtual Spectral Decomposition framework for cancer imaging analysis
AI Now Reads Tumor Slides Like a Radiologist — and Shows Its Work
This review/commentary outlines a Virtual Spectral Decomposition (VSD) methodological framework for analyzing digital pathology and imaging …
A new AI system reads cancer slides like a doctor and explains exactly which biological features drove each diagnosis.
Review of SIMMA utility for paediatric tumour monitoring via cfDNA profiling and ecDNA detection
A Simple Blood Test May Catch Children's Cancer Relapse Months Early
This review evaluates the clinical utility of the SIMMA single-molecule sequencing approach for profiling circulating and cerebrospinal flui…
A single blood or spinal fluid draw can now map a child's tumor DNA at a level of detail that may warn doctors of relapse long before scans …
Review of WGS integration in Emirati genome program reveals high breast cancer variant prevalence and risk stratification utility
Your DNA May Predict Breast Cancer Risk Decades Before Diagnosis
This observational review analyzes whole-genome sequencing data from 436,780 individuals in the Emirati Genome Program to assess breast canc…
A new genome study shows Arab women face higher breast cancer risks than current tools predict, meaning many may need earlier screening.