Meta-analysis finds NLRP3 inflammasome components upregulated in animal depression models
New research links brain inflammation to depression symptoms in animals
This systematic review and meta-analysis of 170 animals (85 depression model, 85 controls) found that protein and mRNA levels of NLRP3, ASC,…
Scientists found that specific inflammation markers rise in the brains of animals with depression, pointing to a new target for future treat…
Meta-analysis identifies moderators of the bidirectional anxiety-alcohol relationship
Age and peer influence link anxiety and alcohol use
This meta-analysis of 55 longitudinal studies examined mediators and moderators in the anxiety-alcohol pathway. Age, externalizing factors, …
Age, peer drinking, and family experiences shape how anxiety and alcohol use are linked, a review of 55 studies finds.
Digital mental health intervention reduces anxiety and depression in Chinese high school students
A 12-week digital program reduced depression and anxiety in Chinese high school students
This 12-week randomized controlled trial in 390 Chinese high school students found that a digital mental health literacy intervention integr…
A 12-week digital program reduced depression and anxiety in Chinese high school students compared to controls, offering a scalable solution …
Systematic review finds aerobic exercise improves executive function in adults with major depressive disorder
Aerobic exercise improves thinking skills in adults with major depression
This systematic review and three-level meta-analysis evaluated aerobic exercise in adults with major depressive disorder. The analysis inclu…
Adults with major depression who exercised regularly showed better focus and mental flexibility. This review found clear benefits for core t…
Meta-analysis reviews psychosis prevalence in bipolar disorder patients across 285 studies
Psychosis common in bipolar disorder, review finds
This meta-analysis reviews data from 285 studies regarding the prevalence of psychosis and psychotic symptoms in patients with bipolar disor…
Nearly half of people with bipolar disorder experience psychosis, and 8% also have schizophrenia, a review of 285 studies finds.
Systematic review and meta-analysis of digital technology interventions for cognitive function and mood in older adults
Digital tools may boost brain health in older adults
This systematic review and meta-analysis evaluated digital technology interventions in older adults with cognitive impairment, depression, a…
Using digital technology like apps or online programs may improve thinking skills and mood in older adults, a new analysis suggests.
Diabetes and social support associations with cognitive impairment in elderly schizophrenia inpatients
Social support and daily living skills linked to lower dementia risk in schizophrenia
This retrospective cross-sectional study of 149 elderly inpatients with schizophrenia found a 47.7% prevalence of cognitive impairment. High…
Nearly half of elderly schizophrenia patients have cognitive impairment. Social support and daily living skills may protect against it.
CBCL-10 shows good diagnostic efficiency for ADHD in a longitudinal cohort study
Shortened checklist shows good efficiency for ADHD diagnosis
This longitudinal cohort study of 1,786 youth evaluated the measurement properties of the Child Behavior Checklist-10 (CBCL-10). The results…
A shorter version of a common behavioral checklist may help clinicians identify ADHD symptoms in children with high accuracy.
Neuroimaging features predict ASD identification and cognitive decoding accuracy in large cohorts
New AI Model Finds Brain Pattern That Predicts Autism Symptoms
This cohort study analyzed individuals from three independent large-scale neuroimaging cohorts (HCP-task, ABIDE-I, ABIDE-II). Cognitive deco…
A new tool finds a clear brain signal that predicts autism symptoms with high accuracy.
Chronic psychosocial stress linked to higher perivascular space volumes in healthy young adults
Stress linked to brain changes in healthy young adults
This cohort study of 61 healthy young adults found that chronic psychosocial stress was associated with significantly higher fractional peri…
Chronic stress may cause subtle brain changes in healthy young adults, a new study finds.
Higher levels of dissociative symptoms observed in individuals with functional neurological disorder
People with FND experience higher levels of dissociation
This pilot study used ecological momentary assessment to compare symptoms between individuals with functional neurological disorder and heal…
New tracking data shows that individuals living with functional neurological disorder report significantly more dissociative symptoms during…
Review of pooled psilocybin data suggests broadening blood pressure eligibility criteria for psychiatric trials
Psilocybin raises blood pressure briefly but stays safe for most patients
This pooled analysis review examined blood pressure and heart rate responses in 368 participants receiving 536 psilocybin sessions at Johns …
New data shows psilocybin raises blood pressure only briefly, suggesting doctors could safely treat more patients with mild high blood press…