GBM model predicts postoperative delirium in elderly CHD patients with 0.856 AUC
Can a computer model predict post-surgery confusion in older heart patients? A new tool shows promise.
A retrospective cohort study of 861 elderly patients with coronary heart disease (CHD) undergoing non-cardiac surgery developed a gradient b…
A new computer tool predicts post-surgery confusion in older heart patients by analyzing frailty, memory, and sleep patterns to help doctors…
Cervical insufficiency associated with higher anxiety and depression scores in second-trimester pregnancy
Does a pregnancy complication make anxiety and depression more likely?
An observational study of 136 second-trimester pregnant women with cervical insufficiency and 117 healthy controls found significantly highe…
Women diagnosed with cervical insufficiency in their second trimester report significantly higher anxiety and depression than those with hea…
Perspective: Bilingualism myths harm autistic children from multilingual families, calls for culturally sustaining interventions
Why are autistic children from multilingual families still told to speak only English at home?
A perspective paper examines how historical misconceptions linking bilingualism with cognitive deficits became embedded in autism interventi…
Autistic children in multilingual families face harmful advice to drop their heritage language, despite proof it supports their development …
Spanish students with disabilities show lower school participation; parents report environmental barriers and supports
Are schools leaving students with disabilities on the sidelines?
An observational survey of 415 Spanish students aged 5–17 years found those with disabilities or special educational needs participated less…
Spanish parents report that cognitive and social demands often stop children with disabilities from fully participating in school activities…
Insomnia's association with cognitive function studied in 170 bipolar disorder outpatients
Study examines link between insomnia and thinking problems in bipolar disorder
An observational study examined 170 outpatients with bipolar disorder to assess insomnia's relationship with cognitive functioning. The abst…
People with bipolar disorder who struggle to sleep may also face thinking problems, though this study only shows a connection without provin…
Chinese CKD Stage 5 HD patients report ~13 symptoms; symptom distress negatively correlates with QoL
What's the biggest struggle for people on dialysis? It's not just physical symptoms — it's worry and sleepless nights.
A multi-center cross-sectional study of Chinese CKD Stage 5 patients on hemodialysis found patients reported an average of 13 symptoms, with…
People on dialysis in China face severe worry, sexual problems, and sleepless nights, with more symptoms directly lowering their quality of …
Case-control study finds no link between Toxoplasma gondii, IFN-γ polymorphism, and paranoid schizophrenia in males
Does a common parasite increase schizophrenia risk in men? New study finds no link.
This case-control study of 103 adult males with paranoid schizophrenia and 102 healthy controls found no evidence that Toxoplasma gondii ser…
A common parasite carried by many people does not increase the risk of schizophrenia in men, according to a new study that found no link bet…
LSD Microdosing Shows Mood Improvement in Major Depressive Disorder: Phase 2a Trial
Can microdosing LSD really boost mood in people with depression?
An open-label trial of microdosed LSD in major depressive disorder showed mood improvements on dosing days (p = 0.009 to 0.039) but no chang…
People with depression taking microdosed LSD for eight weeks reported feeling happier and more creative on dosing days while symptoms droppe…
Phase 2 Trial of Icalcaprant for MDD: Assessing Efficacy and Safety
Could This New Drug Help Ease Severe Depression Symptoms?
A Phase 2 trial is evaluating the efficacy and safety of oral Icalcaprant in 195 adults with MDD. Primary outcomes include changes in MADRS …
A new drug called Icalcaprant is being tested to see if it can help adults with major depressive disorder who are currently experiencing a m…
Ketamine in Orthopedic Trauma: Potential to Reduce Pain and Opioid Use
Could Ketamine Be the Key to Easing Pain and Healing Minds After Surgery?
This Phase 4 trial investigates ketamine's efficacy in reducing postoperative pain and opioid use in orthopedic trauma patients. Primary out…
A new trial tests if giving ketamine during orthopedic surgery reduces pain, opioid needs, and symptoms of depression and PTSD compared to s…
Serum Zinc and Iron Levels Reduced in MDD; Copper Levels Elevated
Could Missing Nutrients Be Worsening Your Depression?
Meta-analysis of 16 studies shows MDD patients have lower serum zinc (SMD = -0.62; 95% CI: -0.78 to -0.46) and iron (SMD = -0.36; 95% CI: -0…
People with depression often have lower zinc and iron but higher copper levels in their blood, suggesting nutrition plays a key role in mana…
Sense of Coherence Tied to Health Factors in Long-Term Impaired Work Ability
Struggling to Work? Your Mental Health Might Be the Key to Recovery.
In a cross-sectional study of 243 patients with long-term sick leave, sense of coherence correlated with health literacy, quality of life, a…
Many people on long-term sick leave face severe anxiety and low quality of life. Improving mental health could help them return to work and …