Case-control study finds no link between Toxoplasma gondii, IFN-γ polymorphism, and paranoid schizophrenia in males
Does a common parasite increase schizophrenia risk in men? New study finds no link
This case-control study of 103 adult males with paranoid schizophrenia and 102 healthy controls found no evidence that Toxoplasma gondii ser…
A common parasite carried by many people does not increase the risk of schizophrenia in men, according to a new study that found no link bet…
LSD Microdosing Shows Mood Improvement in Major Depressive Disorder: Phase 2a Trial
Can microdosing LSD really boost mood in people with depression?
An open-label trial of microdosed LSD in major depressive disorder showed mood improvements on dosing days (p = 0.009 to 0.039) but no chang…
People with depression taking microdosed LSD for eight weeks reported feeling happier and more creative on dosing days while symptoms droppe…
Phase 2 Trial of Icalcaprant for MDD: Assessing Efficacy and Safety
Could This New Drug Help Ease Severe Depression Symptoms?
A Phase 2 trial is evaluating the efficacy and safety of oral Icalcaprant in 195 adults with MDD. Primary outcomes include changes in MADRS …
A new drug called Icalcaprant is being tested to see if it can help adults with major depressive disorder who are currently experiencing a m…
Ketamine in Orthopedic Trauma: Potential to Reduce Pain and Opioid Use
Could Ketamine Be the Key to Easing Pain and Healing Minds After Surgery?
This Phase 4 trial investigates ketamine's efficacy in reducing postoperative pain and opioid use in orthopedic trauma patients.
A new trial tests if giving ketamine during orthopedic surgery reduces pain, opioid needs, and symptoms of depression and PTSD compared to s…
Serum Zinc and Iron Levels Reduced in MDD; Copper Levels Elevated
Could Missing Nutrients Be Worsening Your Depression?
Meta-analysis of 16 studies shows MDD patients have lower serum zinc (SMD = -0.62; 95% CI: -0.78 to -0.46) and iron (SMD = -0.36; 95% CI: -0…
People with depression often have lower zinc and iron but higher copper levels in their blood, suggesting nutrition plays a key role in mana…
Sense of Coherence Tied to Health Factors in Long-Term Impaired Work Ability
Struggling to Work? Your Mental Health Might Be the Key to Recovery
In a cross-sectional study of 243 patients with long-term sick leave, sense of coherence correlated with health literacy, quality of life, a…
Many people on long-term sick leave face severe anxiety and low quality of life. Improving mental health could help them return to work and …