Increased social jetlag is associated with more severe anxiety in adolescents
Irregular sleep patterns linked to more severe anxiety in teens
This meta-analysis of 12 studies involving 235,526 adolescents found a small association between increased social jetlag and more severe anx…
A large study of over 200,000 teenagers shows that inconsistent sleep schedules may be linked to higher levels of anxiety.
Resting-state functional MRI reveals distinct regional homogeneity patterns in MDD, BD, and Schizophrenia
Brain Imaging Reveals Shared Patterns in Depression and Schizophrenia
This meta-analysis of resting-state functional MRI studies identifies specific regional homogeneity (ReHo) abnormalities in patients with MD…
New research identifies specific brain activity patterns that overlap and differ between depression, bipolar disorder, and schizophrenia.
Bipolar disorder is associated with increased cerebrospinal fluid and intracranial volumes compared to controls
Brain structure differences found in people with bipolar disorder
This meta-analysis of adult patients with Bipolar Disorder identifies significant increases in cerebrospinal fluid (CSF) volume, intracrania…
New research shows specific differences in brain fluid and volume in people with bipolar disorder compared to those without the condition.
PGx-guided antidepressants modestly increase short-term response and remission in MDD
Genetic testing may help patients find the right antidepressant
This meta-analysis examines pharmacogenomic-guided antidepressant treatment versus usual care in adults with major depressive disorder. Gene…
Using genetic tests to guide antidepressant choice may help more people with depression find relief during the first few months of treatment…
Autism-related stigma significantly degrades quality of life across mental, physical, and social domains
Autism Related Stigma Linked to Lower Quality of Life
This systematic review of 53 studies examines how various forms of autism-related stigma impact the quality of life for autistic adults and …
Research shows that different types of stigma can negatively impact the physical health, social lives, and mental well-being of autistic adu…
Ketamine modulates NMDA receptors and glutamate transmission for treatment-resistant depression and other psychiatric disorders
Ketamine Shows Potential for Treatment-Resistant Depression and Anxiety
This systematic review synthesizes the pharmacology, network-level effects, and clinical applications of ketamine for conditions including t…
Ketamine may offer new pathways for treating treatment-resistant depression, PTSD, and anxiety by altering brain circuits and signaling.
Antidepressants combined with psychotherapy do not significantly improve depression severity in major depressive disorder
Adding antidepressants to psychotherapy may not improve depression severity
This meta-analysis evaluated the efficacy of adding antidepressants to psychotherapy for patients with major depressive disorder. The analys…
New data suggests that adding antidepressant medication to talk therapy does not necessarily improve depression scores for people with major…
Depression and Schizophrenia Stereotypes Differ in Warmth but Not Competence
People view schizophrenia as less warm than depression
This meta-analysis of 17 studies used the stereotype content model to compare warmth and competence ratings for depression versus schizophre…
New data shows that while people view both conditions as equally capable, they view those with schizophrenia as less warm.
Exercise interventions significantly improve object control, locomotor, and stability skills in children with autism
Exercise improves motor skills for children with autism
This meta-analysis of 31 randomized controlled trials found that exercise interventions significantly improve object control skills (Hedges'…
Exercise programs significantly improve motor skills like balance and movement for children and adolescents with autism spectrum disorder.
Parent and Teacher ADHD Ratings Show Low Agreement, Kappa 0.25 Across 8,796 Youth
Comparing Parent and Teacher Reports for Diagnosing ADHD in Children
This meta-analysis of 8,796 children and adolescents found low overall agreement between parent and teacher ratings of ADHD symptoms (Kappa …
Parents and teachers often see different behaviors in children with ADHD. This study looks at how much these two groups agree on symptoms.
Mass Gathering Preparedness Requires Integrated EMS and Hospital Surge Capacity
Better ways to manage medical emergencies at large public events
This structured narrative review synthesizes 41 papers on mass gathering medical preparedness, focusing on integration of EMS and hospital s…
New research shows that linking emergency services with hospital resources can better manage patient flow during large public gatherings.
Self-medication of ADHD symptoms with psychoactive substances is predominantly inferred from association or motive reports
Mapping the Link Between ADHD and Substance Use Behaviors
This scoping review of 109 sources maps the literature regarding the self-medication of ADHD symptoms with stimulants, cannabis, nicotine, a…
New research maps how adults with ADHD may use substances like nicotine and cannabis to manage symptoms, though evidence remains mostly obse…