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Pulmonology & Critical Care

211 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
CDQ yields highest sensitivity and AUC for identifying patients with chronic obstructive pulmonary disease
Pulmonology & Critical Care Sys. Review
CDQ yields highest sensitivity and AUC for identifying patients with chronic obstructive pulmonary disease New analysis identifies best tools for detecting COPD symptoms
This meta-analysis of 70,693 screened individuals evaluated multiple case-finding approaches for chronic obstructive pulmonary disease (COPD…
A large review identifies specific questionnaires that help doctors more accurately identify patients with chronic obstructive pulmonary dis…
Local ablative therapy integrated with first-line EGFR TKI improves progression-free survival and overall survival
Pulmonology & Critical Care Meta-analysis
Local ablative therapy integrated with first-line EGFR TKI improves progression-free survival and overall survival Adding local treatment to lung cancer drugs improves survival
This systematic review and meta-analysis of 31 studies indicates that integrating local ablative therapy (LAT) with first-line EGFR tyrosine…
Combining local ablative therapy with targeted drugs may help patients with specific lung cancer mutations live longer.
Occupational exposure to asbestos-free talc does not support increased risk of lung or laryngeal cancers
Pulmonology & Critical Care Meta-analysis
Occupational exposure to asbestos-free talc does not support increased risk of lung or laryngeal cancers Talc mining workers show higher risk of certain lung cancers
This meta-analysis evaluated the incidence of lung cancer, mesothelioma, and laryngeal cancer among workers exposed to asbestos-free talc. T…
Workers exposed to asbestos-free talc may face a higher risk of lung cancer, though results for other conditions remain uncertain.
Reactive nodular fibrous pseudotumor presents with distinct immunohistochemical profiles and no progression in patients
Pulmonology & Critical Care Sys. Review
Reactive nodular fibrous pseudotumor presents with distinct immunohistochemical profiles and no progression in patients Identifying Reactive Nodular Fibrous Pseudotumor to Avoid Overtreatment
This case report and literature review characterizes reactive nodular fibrous pseudotumor (RNFP) based on 44 cases. The findings identify sp…
Distinguishing reactive nodular fibrous pseudotumor from actual tumors helps patients avoid unnecessary treatments for certain types of soft…
Immunocompromised Status Associated with Poorer Outcomes in Patients Requiring ECMO for Acute Respiratory Distress Syndrome
Pulmonology & Critical Care Meta-analysis
Immunocompromised Status Associated with Poorer Outcomes in Patients Requiring ECMO for Acute Respiratory Distress Syndrome Comparing ECMO Outcomes for Patients with Weakened Immune Systems and Lung Failure
This meta-analysis examined outcomes for immunocompromised and immunocompetent patients receiving extracorporeal membrane oxygenation for ac…
Patients with weakened immune systems face higher risks when using ECMO for severe lung failure compared to those with healthy defenses.
Delirium prevalence of 41% among patients with acute respiratory distress syndrome
Pulmonology & Critical Care Meta-analysis
Delirium prevalence of 41% among patients with acute respiratory distress syndrome Delirium is common and impacts recovery for patients with ARDS
This meta-analysis of 10,052 ICU patients found a delirium prevalence of 41% (95% CI: 23%-58%) in those with ARDS. While the risk of deliriu…
Nearly half of patients with severe lung distress develop delirium, which can lead to longer hospital stays and more time on breathing machi…
Respiratory trajectories vary by gestational age in infants born before 26 weeks' gestation
Pulmonology & Critical Care RCT
Respiratory trajectories vary by gestational age in infants born before 26 weeks' gestation New data tracks breathing progress for very premature infants
This post-hoc exploratory analysis of a randomized controlled trial involved 601 infants born before 26 weeks' gestation receiving surfactan…
A new look at clinical data helps doctors better predict and manage breathing needs for babies born before 26 weeks of pregnancy.
Non-pharmacologic therapies improve cough in lung cancer; pulmonary rehabilitation may work best
Pulmonology & Critical Care Meta-analysis
Non-pharmacologic therapies improve cough in lung cancer; pulmonary rehabilitation may work best Non-pharmacological Interventions Improve Cough Severity in Lung Cancer Patients
This meta-analysis of 2995 patients with lung cancer found that non-pharmacological interventions, including acupuncture, pulmonary rehabili…
New analysis shows that non-drug treatments like pulmonary rehabilitation can help manage cough and improve quality of life for people with …
Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma
Pulmonology & Critical Care Meta-analysis
Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma Combining Chemotherapy and Immune Therapy Improves Outcomes for Advanced Lung Cancer
This meta-analysis of 3537 patients with advanced pulmonary large-cell neuroendocrine carcinoma (LCNEC) found that chemoimmunotherapy signif…
Adding an immune-boosting drug to standard chemotherapy helps patients with a specific type of advanced lung cancer live longer.
Evaluating Bevacizumab Addition to Atezolizumab Carboplatin and Pemetrexed in Nonsquamous NSCLC
Pulmonology & Critical Care RCT
Evaluating Bevacizumab Addition to Atezolizumab Carboplatin and Pemetrexed in Nonsquamous NSCLC Trial shows bevacizumab addition has mixed results for lung cancer
A Phase III trial assessed adding bevacizumab to a standard triplet regimen for advanced nonsquamous NSCLC, showing no significant OS improv…
A Phase 3 trial found that adding bevacizumab to a standard drug combination did not improve overall survival for most patients with advance…
Rapid on-site evaluation achieves 88.1% sensitivity and 91.7% specificity for lung cancer detection
Pulmonology & Critical Care Meta-analysis
Rapid on-site evaluation achieves 88.1% sensitivity and 91.7% specificity for lung cancer detection Rapid on-site testing improves lung cancer detection during bronchoscopy
This meta-analysis of diagnostic data evaluates the accuracy of rapid on-site evaluation (ROSE) during endobronchial ultrasound-guided bronc…
A new method of checking samples immediately during a procedure helps doctors more accurately identify lung cancer in specific cases.
Lily polysaccharide may mitigate radiation-induced pneumonitis by modulating the gut-lung axis and pulmonary signaling
Pulmonology & Critical Care Sys. Review
Lily polysaccharide may mitigate radiation-induced pneumonitis by modulating the gut-lung axis and pulmonary signaling Lily Polysaccharide May Help Manage Radiation-Induced Pneumonitis
This systematic review explores the potential of Lily polysaccharide (LP) to treat radiation-induced pneumonitis. The authors synthesize evi…
New research explores how lily polysaccharide might protect the lungs from radiation damage by influencing gut health and reducing inflammat…