1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
1 in 7 COPD patients decline or stop breathing therapy
This systematic review and meta-analysis of patients with COPD newly prescribed long-term noninvasive positive airway pressure (PAP) therapy…
A new analysis finds 14% of COPD patients decline or stop long-term breathing therapy, often within six weeks.
Meta-analysis links baseline and dynamic ctDNA to survival in advanced NSCLC
ctDNA in blood predicts survival in advanced lung cancer
This systematic review and meta-analysis of 43 studies found that detectable or elevated baseline plasma ctDNA was associated with worse ove…
A blood test for tumor DNA can predict survival in advanced lung cancer, helping guide treatment decisions.
Pirfenidone reduces lung cancer incidence by 73% in IPF patients with a pooled risk ratio of 0.39
Antifibrotic drugs may lower lung cancer risk in patients with idiopathic pulmonary fibrosis
This systematic review and meta-analysis evaluated antifibrotic therapies in 15582 patients with idiopathic pulmonary fibrosis. The pooled a…
A large review suggests antifibrotic drugs like pirfenidone might lower lung cancer risk in people with idiopathic pulmonary fibrosis, but m…
Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
Immunotherapy before lung cancer surgery is safe, study finds
This meta-analysis of patients with resectable non-small cell lung cancer found that neoadjuvant or perioperative immune checkpoint inhibito…
A new analysis of 2,691 patients shows that immunotherapy before lung cancer surgery is feasible, but comes with specific surgical challenge…
Cutaneous immune-related adverse events associated with improved progression-free survival in non-small cell lung cancer
Skin reactions in lung cancer patients may signal longer life with certain treatments
This meta-analysis evaluated patients with non-small cell lung cancer receiving anti-PD-1, PD-L1, or chemotherapy. The analysis found that c…
A large review found that specific skin reactions linked to cancer drugs are connected to longer survival times for some lung cancer patient…
Irinotecan plus cisplatin shows no RFS benefit over etoposide plus cisplatin in resected lung HGNEC
Five-year follow-up shows irinotecan plus cisplatin matches etoposide plus cisplatin for lung cancer survival
This randomized, open-label, phase III study compared irinotecan plus cisplatin to etoposide plus cisplatin in 221 patients with resected hi…
A five-year look at lung cancer patients found that irinotecan plus cisplatin worked just as well as etoposide plus cisplatin for keeping th…
Metabolomics profiles show elevated phenylalanine and lactate alongside depleted sphingosine 1-phosphate and citrulline in ARDS patients
Metabolomics profiles reveal metabolic signatures in patients with acute respiratory distress syndrome
This systematic review and meta-analysis examines metabolomics profiles in patients with acute respiratory distress syndrome compared to tho…
A new analysis shows specific chemical changes in the blood of patients with acute respiratory distress syndrome compared to those without t…
Respiratory microbiome composition in children offers new ideas for precision treatment of respiratory diseases and asthma
New ideas for treating children with asthma and respiratory infections
This narrative review examines the respiratory microbiome, metabolites, and colonization in children with respiratory infections, allergic a…
This review offers fresh directions for understanding how the respiratory microbiome affects children with asthma and allergic airway inflam…
Systematic review links specific TCM constitutions to worse COPD outcomes in 2,168 patients
TCM Constitution Types Linked to Worse COPD Outcomes
This systematic review and network meta-analysis examined Traditional Chinese Medicine (TCM) constitutions in 2,168 COPD patients. The autho…
A large analysis of 2,168 COPD patients found that specific Traditional Chinese Medicine constitution types were linked to lower lung functi…
Subcutaneous astegolimab reduced COPD exacerbations in phase 2b and 3 trials versus placebo
New drug cuts COPD flare-ups for some smokers in large trials
This randomized, double-blind, placebo-controlled phase 2b and 3 trial evaluated subcutaneous astegolimab in current or former smokers with …
A new medicine called astegolimab reduced severe breathing flare-ups for some people with COPD, though results varied by how often they took…
Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery
3-year-old girl with TP53 mutation and bilateral Wilms tumor died after treatment
This case-based review describes a single 3-year-old girl with bilateral Wilms tumor and a TP53 mutation treated under the Chinese Children …
A single case report describes a 3-year-old girl with bilateral Wilms tumor and a TP53 mutation who died despite aggressive chemotherapy and…
Delayed arousal timing links to higher mortality in sleep apnea patients
Timing of breathing pauses predicts death risk in obstructive sleep apnea
A meta-analysis found that each one-second delay in post-apnea arousal peak time was associated with increased all-cause and cardiovascular …
New analysis shows how late a breathing pause wakes you up predicts higher death risk for men with obstructive sleep apnea.