Review of animal models shows unclear causal links between microbial dysbiosis and pulmonary fibrosis
Your Gut Microbes May Shape Lung Fibrosis Treatment
This review examined animal models regarding pulmonary fibrosis.
Your gut microbes may influence lung scarring, opening new paths for treatment beyond current drugs.
Subcutaneous tislelizumab shows comparable trough concentrations to intravenous dosing in treatment-naive advanced non-small cell lung cancer patients
Phase I trial shows subcutaneous tislelizumab reaches high drug levels in lung cancer patients
This phase I trial evaluated subcutaneous versus intravenous tislelizumab in treatment-naive patients with advanced non-small cell lung canc…
Early data suggest subcutaneous tislelizumab injections may offer similar drug levels to intravenous forms for treating advanced lung cancer…
RNK08954 shows unconfirmed responses in KRASG12D-mutant NSCLC and PDAC in Phase Ia trial
New drug shows promise for KRASG12D lung and pancreatic cancers
This phase Ia trial evaluated RNK08954 in 36 patients with KRASG12D-mutant non-small cell lung cancer or pancreatic ductal adenocarcinoma.
An early trial of RNK08954 shrank tumors in 58% of lung cancer patients with a specific KRAS mutation.
Pulmonary barotrauma incidence and risk factors in non-HIV PCP patients
Researchers find oxygen ratio predicts lung injury in pneumonia patients
This single-center retrospective cohort study of 334 non-HIV patients with Pneumocystis jirovecii pneumonia found that 12.0% developed pulmo…
A new model helps identify pneumonia patients at higher risk for severe lung complications using oxygen levels and blood markers.
LSTM analysis of infant tidal breathing detects bronchopulmonary dysplasia with 97% accuracy
New AI tool reads baby breath to spot lung disease early
This cohort study of 329 infants and 135 school-age children used recurrent neural networks to analyze tidal breathing flow time series.
A new computer model can read a baby's simple breathing pattern to find lung disease before it becomes serious.
Review of CFTR modulator impact on cystic fibrosis outcomes from registry data
Cystic Fibrosis Patients See Lung Function Jump Over a Decade
This review and synthesis of Cystic Fibrosis Foundation Patient Registry data describes trends in adults with cystic fibrosis from 2011 to 2…
A decade of registry data shows lung function and weight improved for adults with cystic fibrosis as newer modulator therapies became availa…
Smartphone app-based music PR program improves walking distance in COPD patients
Smartphone app with singing helps COPD patients walk farther
This multicenter randomized controlled trial in 70 patients with COPD found that a smartphone app-based, music-facilitated multicomponent pu…
A new phone app that mixes singing with walking helps people with COPD breathe easier and walk farther than usual care.
Review synthesizes pilot data on nasal microbiota and respiratory outcomes in infants
Nasal bacteria clues could predict infant wheezing risks early
This review synthesizes findings from a pilot observational study involving 55 infants enrolled in the AERIAL study.
Specific nose bacteria might predict wheezing risks for babies during their first year of life soon enough now.
Systematic review and meta-analysis of pharmacist-led care in COPD
Pharmacist Care Cuts Hospital Visits for COPD
This systematic review and meta-analysis of 2313 COPD patients synthesized evidence on pharmacist-led interventions.
Getting a pharmacist to manage your COPD care plan could significantly reduce your chances of ending up in the hospital.
Narrative review discusses tumor draining lymph nodes as a target for NSCLC therapy
Lymph Nodes Hold Key to Beating Lung Cancer
This narrative review examines the tumor draining lymph nodes (TDLN) microenvironment remodeling in non-small cell lung cancer (NSCLC).
You wake up, sip your coffee, and take your morning walk.
Host transcriptional biosignatures for TB progression in Indian household contacts
Blood test signatures may help predict TB in household contacts
This observational cohort study of 525 Indian household contacts of TB patients evaluated host transcriptional biosignatures for predicting …
A study in India found that blood-based gene signatures could help identify household contacts at risk of developing tuberculosis, but perfo…
Meta-analysis of 15 observational studies links e-cigarette use to higher COPD odds
E-Cigs Linked to Higher COPD Risk Even Without Smoking
This meta-analysis of 15 observational studies assessed the association between e-cigarette use and the prevalence of chronic obstructive pu…
Using e-cigarettes today is connected to a much higher chance of developing COPD, even if you have never smoked a regular cigarette before.