Preoperative femoral nerve block reduces rebound pain after knee arthroplasty versus postoperative block
Give Nerve Block Before Surgery To Stop Pain
In an RCT of 186 patients undergoing total knee arthroplasty, preoperative femoral nerve block with ropivacaine reduced rebound pain inciden…
Getting a pain-numbing shot before knee surgery cuts rebound pain in half, helps patients sleep better, and reduces the need for strong pain…
China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021
A Silent Wave of Disability is Rising. Here’s Who’s Most at Risk
This cross-sectional analysis of data from China between 1990 and 2021 examined rehabilitation needs for ten neurological conditions, includ…
China faces a rising wave of neurological disability driven by aging, with stroke, Alzheimer's, and Parkinson's creating urgent long-term ca…
ESD achieves R0 resection for large rectal intramucosal carcinoma involving dentate line in case report
Imagine a large, pre-cancerous growth in the most sensitive part of your rectum. Removing it used to mean major, life-altering surgery. But a new report shows a different path is possible
A case report describes a 70-year-old male with altered bowel habits who underwent endoscopic submucosal dissection for a large rectal tumor…
Doctors successfully removed a large, tricky rectal tumor with a minimally invasive technique, preserving the patient's natural bowel functi…
Untargeted urinary proteomics identifies dysregulated biomarkers in women with endometrial cancer versus controls
New Urine Test Could Spot Endometrial Cancer Early
This case–control study evaluated untargeted label-free LC-MS/MS mass spectrometric approaches combined with bioinformatics in 40 women (20 …
A new urine test analyzes hundreds of proteins to spot endometrial cancer early without invasive biopsies.
Guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation
A New Strategy Emerges to Stop Liver Cancer From Coming Back
A guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation.
Doctors are finding smarter ways to use the body’s own immune system around the time of surgery to give patients with liver cancer a better …
Biological DMARDs show marginal patient-reported outcome benefits over conventional therapy in early rheumatoid arthritis
Early rheumatoid arthritis patients report similar symptom relief with different treatment approaches
This open-label randomized trial in 795 newly diagnosed, DMARD-naïve RA patients compared three biological DMARDs plus methotrexate against …
In early rheumatoid arthritis, patients reported similar pain relief and quality-of-life improvements whether they started with conventional…
Anifrolumab shows higher remission rates versus placebo in SLE patients regardless of immunosuppressant history
A New Lupus Drug May Work Better If You Start It Sooner
A post hoc analysis of pooled Phase 3 RCT data in 726 patients with moderate-to-severe SLE found higher DORIS remission rates with anifrolum…
Starting a new lupus drug before trying older medications may help patients reach remission faster and with fewer side effects.
VATS and hormonal therapy for diaphragmatic endometriosis in a 42-year-old woman with hepatic herniation
Can surgery alone fix rare chest pain caused by endometriosis, or is a team approach needed?
This case report and literature review describes a 42-year-old woman with diaphragmatic endometriosis, hepatic herniation, and catamenial pn…
A 42-year-old woman's rare chest pain from endometriosis required both surgery and hormones, proving that surgical repair alone may not be e…
Antimicrobial peptides show anticancer activity via membrane disruption and immune priming in preclinical models
Review finds antimicrobial peptides show promise against cancer cells but clinical evidence remains limited
A systematic review of preclinical evidence finds antimicrobial peptides (AMPs) exhibit selective electrostatic interactions with malignant …
Antimicrobial peptides can selectively target and kill cancer cells by disrupting their membranes while also acting as vaccines to boost the…
Functional precision medicine approaches may complement current paradigms for non-metastatic colorectal cancer management
Your Colon Cancer Treatment Plan May Be Missing This One Crucial Piece
This commentary discusses functional precision medicine approaches, genomic profiling, and ex vivo drug responses in patients with non-metas…
Standard colon cancer plans often miss unique biology that drives recurrence, prompting calls for new approaches beyond current guidelines.
Proceeding with TKA without preoperative anticoagulation for asymptomatic calf vein thrombosis shows no 90-day VTE events
Skip the delay for a minor clot before knee surgery
A retrospective cohort study of 454 adults undergoing primary unilateral TKA found that 44 patients with preoperative asymptomatic isolated …
A small, silent clot found before knee replacement does not require stopping surgery or adding extra blood thinners.
Retrospective study identifies predictors of prolonged ventilation after basal ganglia hemorrhage surgery
One in Three Brain Bleed Patients Face Weeks on a Ventilator — Who's Most at Risk?
A retrospective cohort study of 173 adult ICU patients who underwent surgery for hypertensive basal ganglia intracerebral hemorrhage found t…
About one in three patients recovering from brain bleed surgery need a breathing machine for two weeks or longer, with older age and kidney …