Modified anal fistula plug with drainage seton shows early recovery benefits and comparable 12-month outcomes to conventional treatment in cryptoglandular anal fistula
A New Plug for Anal Fistulas Cuts Pain and Speeds Healing
This prospective cohort study evaluated 140 patients with cryptoglandular anal fistula treated with a modified anal fistula plug combined wi…
A modified anal fistula plug helps patients heal faster with less pain after surgery, offering a smoother recovery for those dealing with th…
PRO and Serum Biomarker Models Predict Endoscopic Activity in Ulcerative Colitis
Count Your Stools to Spot Flare-Ups Early
A retrospective multicenter cohort study of 297 UC patients developed models using patient-reported outcomes (stool frequency, rectal bleedi…
Counting your daily stools and bleeding can accurately spot ulcerative colitis flare-ups without needing an invasive colonoscopy.
Retrospective cohort finds 25-gauge vitrectomy achieves complete foreign body removal in all 198 eyes
What happens when metal enters the eye? A surgery study shows who gets hurt
A retrospective cohort of 198 patients undergoing 25-gauge pars plana vitrectomy for intraocular foreign body (IOFB) extraction achieved 100…
A study of nearly 200 eye injuries found metal objects were removed in every surgery, with most patients being young or middle-aged men in r…
Regional anesthesia with propofol sedation versus general anesthesia in unilateral total knee arthroplasty patients
Numb Legs, Faster Walks: New Knee Surgery Data
This retrospective cohort study evaluated 250 patients undergoing unilateral total knee arthroplasty to compare regional anesthesia with mon…
New knee surgery data shows regional anesthesia leads to faster walking and fewer readmissions without increasing dangerous blood clot risk.
Combined radiomics-clinical model improves AP for differentiating pulmonary tuberculosis from non-tuberculous lung lesions on CT
New CT model may help distinguish tuberculosis from other lung lesions in some patients
This observational study evaluated 900 patients with pulmonary tuberculosis or non-tuberculous solid lung lesions.
A new computer model using CT scans and clinical data outperforms standard methods in distinguishing tuberculosis from other lung lesions in…
Post-hoc analysis of RCTs and cohorts identifies predictors of remission in ACPA-positive early RA treated with abatacept plus methotrexate or methotrexate alone
Early disease activity and response predict remission in ACPA-positive rheumatoid arthritis patients
This post-hoc analysis of randomized controlled trials and an observational cohort evaluated predictors of DAS28-CRP remission in ACPA-posit…
Only early disease activity and treatment response predict remission in ACPA-positive rheumatoid arthritis, while genetic markers and imagin…
Hand massage improves grip strength and function in early RA patients in pilot trial
Can hand massage improve grip strength and reduce pain in early rheumatoid arthritis?
A pilot randomized controlled trial of 30 female RA patients with low disease activity found that 10 hand massage sessions over 2 weeks sign…
Ten hand massage sessions boosted grip strength and lowered pain for women with early rheumatoid arthritis, while standard care alone showed…
Hydroxychloroquine did not prevent SLE progression in incomplete lupus patients in randomized trial
Hydroxychloroquine did not slow disease progression in incomplete lupus patients over two years
A randomized, double-blind trial of 180 patients with incomplete lupus erythematosus found hydroxychloroquine did not reduce progression to …
Hydroxychloroquine failed to slow lupus progression in patients with early symptoms over two years, matching placebo results.
Vedolizumab plus curcumin improves remission in moderate-to-severe ulcerative colitis versus vedolizumab alone
Could adding curcumin to your current ulcerative colitis treatment help you reach remission faster?
This multicenter, double-blind randomized controlled trial enrolled 159 patients with moderate-to-severe ulcerative colitis.
Adding curcumin to ulcerative colitis treatment helped more patients reach symptom remission faster than using standard drugs alone.
Rh five-antigen-matched transfusions associated with lower alloimmunization in patients needing repeated RBC transfusions
Could a more precise blood match reduce risks for people needing frequent transfusions?
An RCT in patients requiring multiple RBC transfusions found Rh five-antigen-matched transfusions were associated with significantly lower i…
Patients needing frequent transfusions face fewer reactions, shorter hospital stays, and less blood used with a more precise blood match str…
Subcutaneous etanercept rapidly alleviated pain and inflammation in 12 acute gout patients compared to methylprednisolone
Small study finds etanercept may help acute gout pain like steroids
This single-center, prospective, randomized, open-label study evaluated subcutaneous etanercept versus intravenous methylprednisolone in 12 …
A small study found etanercept provided rapid pain relief for acute gout flares that matched standard steroid treatment with no serious side…
Systematic review identifies shared immune mechanisms and therapeutic targets across cardiovascular inflammatory diseases
Could one immune problem be driving three different heart conditions?
A systematic review examined shared immunological mechanisms across atherosclerosis, myocarditis, and vasculitis.
Three different heart diseases might share one immune trigger, suggesting new ways to treat plaque buildup, heart muscle inflammation, and b…