Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
High-dose antibiotic shows partial skull base infection resolution
This case report describes an 84-year-old man with type 1 diabetes, vascular comorbidity, and advanced frailty treated for skull base osteom…
An 84-year-old man with diabetes and a rare skull infection saw some improvement with a long antibiotic course, but his condition remained c…
Narrative review offers practical guidance for diagnosing and managing emergency rheumatic disease in children
Guidance for managing emergency rheumatic disease in childhood
This narrative review addresses the diagnosis and management of emergency rheumatic disease in the pediatric population. The authors provide…
This narrative review offers practical guidance for diagnosing and managing emergency rheumatic disease in children within pediatric rheumat…
Review of 16 cases shows 25% mortality for pulmonary mucormycosis in DKA patients treated with amphotericin B
Treatment for rare lung infection kills one in four patients with diabetic ketoacidosis
This case report and literature review synthesizes data from 16 patients with diabetic ketoacidosis complicated by invasive pulmonary mucorm…
A review of 16 patients found that one in four died from this rare lung infection. Early diagnosis and surgery are key.
Case report and literature review on IgG4-related disease misdiagnosed as pancreatic cancer in a 70-year-old male
A 70-year-old man avoided unnecessary surgery after doctors found a treatable autoimmune condition
This case report and literature review examines a 70-year-old male patient with IgG4-related autoimmune pancreatitis initially suspected as …
A 70-year-old man with a pancreatic mass was found to have a treatable autoimmune disease, sparing him from unnecessary surgery.
Systematic Review of Schisandra chinensis for Metabolic Dysfunction-Associated Steatotic Liver Disease
Ancient herb shows promise for fatty liver disease
This systematic review summarizes preclinical evidence on Schisandra chinensis Fructus (SCF) and its metabolites for metabolic dysfunction-a…
A systematic review finds Schisandra chinensis may protect the liver and reduce fat buildup, but evidence is still early.
Meta-analysis of ROP treatments finds anti-VEGF linked to less myopia than laser or surgery
Anti-VEGF Treatment Leads To Better Vision Outcomes For Premature Babies
This systematic review and meta-analysis of 10,269 eyes found anti-VEGF treatment for retinopathy of prematurity was associated with the lea…
New research shows that anti-VEGF injections lead to better long-term vision for premature babies than laser or freezing methods.
Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
New drug strategy targets mouth cancer's hidden power source
This narrative review discusses the potential of mitochondrial-targeted therapeutics in oral squamous cell carcinoma (OSCC). The authors syn…
Targeting the cell's power source could help overcome stubborn mouth cancer resistance.
Meta-analysis shows AI virtual patient simulations improve psychiatric interview training in health professions education
AI Virtual Patients Boost Psychiatric Interview Skills
This meta-analysis synthesizes evidence from approximately 450 participants across 10 studies in health professions education. The authors r…
New AI tools help train doctors to talk better to patients with mental health issues by simulating real conversations.
Enpatoran fails to show dose-response in moderate-to-severe SLE phase 2 trial
New Lupus Drug Shows Promise But Misses Key Target in Trial
This phase 2 RCT enrolled 354 adults with moderate-to-severe SLE. Enpatoran (25, 50, or 100 mg twice daily) did not show a statistically sig…
A new daily pill for lupus called enpatoran helped more patients get relief from their symptoms, but the drug didn't hit the statistical tar…
Narrative review suggests MRgFUS reduces lesion size and symptoms in women with adenomyosis
Magnetic resonance-guided focused ultrasound surgery helps reduce lesion size and ease symptoms for women with adenomyosis
This narrative review examines magnetic resonance-guided focused ultrasound surgery (MRgFUS) for adenomyosis in women of childbearing age. T…
This review explains how magnetic resonance-guided focused ultrasound surgery can shrink problem areas and relieve pain for women with adeno…
Narrative review explores m6A modification and metabolic reprogramming in rheumatoid arthritis
Rheumatoid Arthritis May Start With a Tiny Chemical Tag on Your Genes
This narrative review examines the role of m6A modification in metabolic reprogramming during rheumatoid arthritis pathogenesis. The authors…
A hidden chemical switch in your cells may drive rheumatoid arthritis by turning on inflammation and joint damage.
Review of SC-EVs for SLE and MS highlights immunomodulatory mechanisms and neuroprotective potential
New cell-free therapy could calm immune fires in lupus and MS
This narrative review examines stem cell-derived extracellular vesicles (SC-EVs) for systemic lupus erythematosus and multiple sclerosis. Th…
Tiny cargo from stem cells might stop the immune system from attacking the brain and joints in lupus and MS patients