Digital support for exercise improves physical function in knee osteoarthritis patients
Different Exercise Styles Show Varying Results for Knee Osteoarthritis
This systematic review and network meta-analysis of 2,250 patients evaluated seven exercise and self-management strategies for knee osteoart…
New research looks at how different types of exercise and digital support impact pain and movement for people with knee osteoarthritis.
Somalia's infectious disease surveillance shows improved facility reporting but remains weak in investigation and response
Somalia's outbreak alerts often go unverified, review finds
This narrative review evaluates Somalia's infectious disease surveillance and outbreak preparedness systems against International Health Reg…
Somalia improved disease reporting, but verifying alerts and confirming cases in labs lag far behind, a review finds.
Inflammation and fibrosis coupling contribute to hair follicle miniaturization in androgenetic alopecia
Inflammation and Fibrosis Linked to Hair Loss in Male Pattern Baldness
This mini-review explores the role of inflammation and fibrosis in androgenetic alopecia. The authors identify specific immune-enriched tran…
New research highlights how inflammation and tissue scarring may play a key role in why some people experience hair loss in androgenetic alo…
Nitrogen dioxide exposure is associated with increased risk of cataract outcomes in meta-analysis
Air Pollution Linked to Increased Risk of Cataracts
This meta-analysis evaluates the association between air pollution markers and cataract outcomes. The analysis found a significant associati…
New research suggests that exposure to common air pollutants like nitrogen dioxide may be linked to a higher risk of developing cataracts.
Surgical treatment for tophaceous gout linked to 24% overall complication rate in meta-analysis
Surgical Treatment for Gout Carries Specific Risks for Patients
This meta-analysis of 18 retrospective studies examined postoperative outcomes after surgical treatment for tophaceous gout. Pooled rates we…
Surgery for tophaceous gout is linked to risks like infection and wound healing delays, which is important for patients planning for treatme…
Prolactin and estradiol levels are elevated in patients with active systemic lupus erythematosus
Hormone levels vary in people with systemic lupus erythematosus
This meta-analysis of 5389 individuals with systemic lupus erythematosus (SLE) found significantly higher prolactin and estradiol levels in …
New data shows that people with systemic lupus erythematosus often have different hormone levels, especially during active periods of the di…
Decolonizing Nigerian medical education faces structural barriers and a disconnect from global scholarship terminology
Nigerian Medical Education Faces Challenges in Global Decolonization Efforts
This narrative review explores the decolonization of health professions education within the Nigerian context. It identifies significant bar…
Nigerian medical education faces unique hurdles in decolonization due to historical ties to European systems and a gap in global academic re…
Higher mycophenolic acid levels correlate with 12-fold higher odds of clinical response in SLE
Higher Mycophenolic Acid Levels Linked to Better Lupus Response
This systematic review and meta-analysis of 24 studies indicates that higher mycophenolic acid (MPA) levels are associated with improved cli…
Higher levels of the medication mycophenolic acid are linked to better clinical responses in patients with systemic lupus erythematosus.
Immune-cell activation and metabolic dysfunction may interact to influence synovial inflammation and cartilage homeostasis in osteoarthritis
Immune and Metabolic Signals Linked to Osteoarthritis
This narrative review explores the interplay between immune and metabolic processes in osteoarthritis. The authors suggest that these intera…
Osteoarthritis may involve a two-way conversation between immune cells and metabolism, a new review suggests.
Rituximab-based therapy associated with moderate renal response and reduced proteinuria in relapsing lupus nephritis
Rituximab Shows Promise for Managing Difficult Lupus Nephritis Cases
This meta-analysis of 445 patients evaluated rituximab-based rescue or add-on therapy for relapsing or refractory lupus nephritis. The analy…
Rituximab may help manage kidney damage in patients with difficult-to-treat lupus nephritis by improving renal response and lowering protein…
Galectin-3 levels elevated in SLE with mean difference 8.48 versus healthy controls
Higher levels of galectin-3 linked to systemic lupus erythematosus
This meta-analysis synthesizes evidence on circulating galectin-3 levels in individuals with systemic lupus erythematosus compared with heal…
A protein called galectin-3 is found in much higher amounts in people with systemic lupus erythematosus than in healthy people.
Stigma affects nearly half of adults with SLE, pooled prevalence 46%
Nearly half of people with lupus face social stigma
This meta-analysis of observational studies estimates the prevalence and determinants of stigma in adults with systemic lupus erythematosus.…
Living with lupus can mean facing hidden layers of discrimination and social stigma that impact mental health and daily life.