Inflammation and fibrosis circuits drive tissue remodeling and neurogenic inflammation in endometriosis
Fibrosis and Inflammation Link to Endometriosis Pain and Infertility
This mini review explores the role of the inflammation-fibrosis circuit in endometriosis, highlighting how cyclic bleeding and tissue remode…
New research highlights how a cycle of inflammation and tissue scarring may drive the pain and fertility issues seen in endometriosis.
Tumor necrosis factor inhibition is associated with improvements in CNS-related outcomes in rheumatoid arthritis
Tumor necrosis factor inhibitors may help brain symptoms in rheumatoid arthritis
This narrative review explores the joint-brain framework in rheumatoid arthritis, synthesizing preclinical and clinical evidence regarding n…
New research suggests that treating inflammation in rheumatoid arthritis may help with brain-related issues like fatigue, pain, and mood cha…
Scoping review protocol to map catheter management practices in long-term care
Catheter Care in Long-Term Care: Review Protocol Launches
This is a protocol for a scoping review, not a completed study. It outlines a plan to map evidence-informed practices and work system factor…
A new plan outlines how researchers will map evidence on catheter use in long-term care homes.
Tumor dormancy creates a reservoir of drug tolerance and may trigger disease relapse in cancer
Dormant cancer cells may hide and cause disease to return
This systematic review explores the mechanisms of tumor dormancy and its role in cancer recurrence. The authors conclude that dormant cells …
Hidden cancer cells can stay quiet and resist standard treatments like surgery or chemo, potentially causing the disease to return later.
Neural network approaches reduce RMSE by 60% in robotic-assisted beating heart surgery motion compensation
Robotic Surgery Technology Shows Promise for Beating Heart Procedures
This scoping review of 61 studies evaluates active closed-loop algorithmic motion compensation for robotic-assisted minimally invasive cardi…
New robotic motion compensation technology aims to stabilize heart surgery, though it has not yet been tested in human clinical trials.
FDA Approves Yusimry (adalimumab) for Multiple Inflammatory Conditions
FDA Approves Yusimry for Several Inflammatory Conditions
The FDA has approved Yusimry, a tumor necrosis factor blocker, for rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis,…
The FDA has approved Yusimry, a new injectable drug for chronic inflammatory conditions like rheumatoid arthritis, Crohn's disease, and plaq…
FDA Approves Olumiant (baricitinib) for Moderately to Severely Active Rheumatoid Arthritis
FDA Approves New Once-Daily Pill for Tough Rheumatoid Arthritis Cases
The FDA has approved Olumiant (baricitinib) for adults with moderately to severely active rheumatoid arthritis who have had an inadequate re…
The FDA approved Olumiant (baricitinib) for adults with moderate to severe rheumatoid arthritis who did not get enough relief from TNF block…
GLP-1 Receptor Agonists for MASH: Protocol Aims to Synthesize Histological and Metabolic Outcomes
New plan to study GLP-1 drugs for fatty liver disease
This is a protocol for a systematic review and meta-analysis evaluating GLP-1 receptor agonists versus placebo or standard care in adults wi…
A new research plan aims to see if GLP-1 medications can improve liver health and reduce scarring in adults with MASH.
Competency-based medical education assessment tools face challenges in validity, equity, and faculty readiness in anesthesiology
New Assessment Tools Aim to Improve Anesthesiology Training Quality
This narrative review examines competency-based medical education (CBME) assessment tools, including milestones and entrustable professional…
New assessment tools for anesthesiology residents aim to improve training, but experts note that teacher training and tool reliability remai…
Perioperative IV lidocaine cuts chronic postsurgical pain at 3 months but not 6 months
Lidocaine during surgery may reduce chronic pain after operations
This systematic review and meta-analysis of 1,391 adults found that perioperative intravenous lidocaine significantly reduced chronic postsu…
Giving patients lidocaine during surgery may lower the risk of developing chronic pain three months after a procedure.
Diagnostic codes and algorithms show 0.90 sensitivity for identifying systemic lupus erythematosus in electronic records
Electronic Records Help Identify Connective Tissue Diseases More Accurately
This meta-analysis of 38 studies evaluates the accuracy of electronic health record codes and algorithms for identifying connective tissue d…
New data shows that specific coding systems in electronic health records can accurately identify patients with several connective tissue dis…
Hypertension and acute kidney dysfunction are common clinical manifestations in pediatric acute post-streptococcal glomerulonephritis
Common kidney complications for children after strep throat infections
This meta-analysis of 18 studies involving 2,191 children identifies common clinical manifestations in acute post-streptococcal glomerulonep…
A large review of over 2,000 children shows that high blood pressure and kidney issues are common after strep infections.