Atypical granular cell tumor requires immunohistochemical detection and multimodal imaging to avoid common misdiagnosis as schwannoma
Rare Thigh Tumor Diagnosed With Imaging and Biopsy
This case report and literature review describes an atypical granular cell tumor in a 49-year-old male. The authors highlight that while the…
A man's thigh mass turned out to be a rare granular cell tumor, highlighting the need for careful diagnosis.
TCM influenza research surges after 2020, shifting from clinical practice to mechanistic studies
Traditional Chinese Medicine Research on Influenza Surges After 2020
A systematic bibliometric analysis of 1,527 publications maps the landscape of Traditional Chinese Medicine (TCM) research on influenza. The…
A review of 1,527 publications shows TCM research for influenza has grown rapidly since 2014, with a sharp rise after 2020. China leads in o…
CAR-T cell therapy for lymphoid malignancies presents a biphasic pattern of infectious complications
CAR-T Cell Therapy Shows Specific Patterns of Infection Risks
This narrative review examines the incidence patterns of bacterial, viral, and opportunistic infections in patients receiving CAR-T cell the…
Patients receiving CAR-T cell therapy for lymphoid malignancies may face different types of infections during early and late stages of treat…
Six paradigm shifts reframe preeclampsia as a first-trimester villous trophoblast syndrome
New Research Reframes the Origins of Preeclampsia
This narrative review synthesizes six inter-related paradigm shifts in placental pathophysiology, reframing preeclampsia as a first-trimeste…
New research suggests preeclampsia begins in the first trimester, potentially allowing for earlier detection and more diverse ways to assess…
Sulbactam-durlobactam and tigecycline provide clinical improvement for polymicrobial infections in severe acute pancreatitis
New drug combination shows promise for severe pancreatic infections
This case report describes the use of sulbactam-durlobactam and tigecycline for a 51-year-old male with severe acute pancreatitis and organ …
A new antibiotic combination helped a patient with a life-threatening infection that was resistant to many common drugs.
Combination therapies of plant-derived compounds outperform monotherapy for psoriasis vulgaris with specific immunological profiles
Plant compounds combined with standard care improve psoriasis symptoms
This systematic review and network meta-analysis of 84 randomized controlled trials involving 7,544 patients found that combination therapie…
Combining specific plant-derived ingredients with standard treatments may offer better results for people living with psoriasis.
EMG-based bioelectrical feedback improves Fugl-Meyer scores by 9.50 points in post-stroke hemiplegia
Bioelectrical Feedback Improves Motor Function After Stroke
This systematic review and meta-analysis of 8 studies found that EMG-based bioelectrical feedback significantly improved motor function comp…
A review of clinical data shows that bioelectrical feedback can improve motor skills and daily activities for people with post-stroke hemipl…
Continuous renal replacement therapy may support metabolic and circulatory stability in preterm infants with AKI
CRRT Treatment Shows Promise for Infants with Kidney Injury
This case report and literature review describes the use of continuous renal replacement therapy (CRRT) for a very low birth weight preterm …
A new case report highlights how continuous renal replacement therapy may help stabilize very low birth weight infants facing acute kidney i…
Avacopan is associated with high remission rates and low relapse in ANCA-associated vasculitis
Avacopan shows high remission rates for ANCA-associated vasculitis
This systematic review and meta-analysis of 71 studies indicates that avacopan is associated with an 87% remission rate at 6 months and a 93…
New data shows avacopan helps many patients with ANCA-associated vasculitis reach remission while reducing the need for steroid use.
Tebentafusp provides modest survival benefit and manageable safety profile in metastatic uveal melanoma
Trial Shows Tebentafusp Offers Survival Benefit for Metastatic Uveal Melanoma
This systematic review and meta-analysis of 631 patients evaluates tebentafusp for metastatic uveal melanoma. The analysis found an overall …
Tebentafusp shows a modest survival benefit for patients with metastatic uveal melanoma, despite low response rates and manageable side effe…
Enteral immunonutrition reduces infectious complications and hospital stay duration in gastric cancer surgery
Specialized Nutrition May Reduce Complications After Gastric Cancer Surgery
This meta-analysis of randomized controlled trials involving 1,653 patients found that enteral immunonutrition (EIN) significantly reduced i…
Patients undergoing gastric cancer surgery may experience fewer complications and shorter hospital stays when using a specific type of enric…
Bio-inductive collagen scaffolds improve structural integrity but show inconsistent translation to patient-perceived gains
Scaffolds May Improve Structural Integrity in Rotator Cuff Tears
This clinical guideline reviews the use of bio-inductive collagen scaffolds for rotator cuff repair. The authors synthesize evidence showing…
New scaffolds can improve the physical structure of rotator cuff repairs, but these structural gains do not always lead to better results fo…