Ofloxacin shows superior relative efficacy for pain control after photorefractive keratectomy
Topical and systemic drugs help manage pain after eye surgery
This systematic review and network meta-analysis of 2,797 patients evaluated pharmacological strategies for post-photorefractive keratectomy…
New data identifies specific medications that rank highest for managing patient pain following photorefractive keratectomy eye procedures.
Intraoperative intravenous methadone reduces 24-h pain intensity and opioid consumption after cardiac surgery
Methadone May Reduce Pain After Cardiac Surgery
This meta-analysis of 10,203 patients found that intraoperative intravenous methadone is associated with lower postoperative 24-h pain inten…
Intraoperative methadone may lead to lower pain levels and less opioid use during the first 24 hours following cardiac surgery.
Chinese medicine external therapies show varying efficacy for symptoms in diarrhea-predominant irritable bowel syndrome
Chinese medicine therapies show promise for irritable bowel syndrome
This systematic review and network meta-analysis evaluates Chinese medicine external therapies (CMETs) for patients with IBS-D. The analysis…
New research suggests specific Chinese medicine techniques like moxibustion and electroacupuncture may help manage symptoms of irritable bow…
Psoriasis patients with moderate to severe disease show higher prevalence of type 2 diabetes
Psoriasis patients face higher risk of type 2 diabetes
This narrative review explores the link between psoriasis and type 2 diabetes mellitus, highlighting shared inflammatory pathways and metabo…
People with psoriasis are more likely to develop type 2 diabetes because both conditions share common pathways of chronic inflammation.
Pulmonary TB History Linked to Higher COPD Odds
Past tuberculosis infection significantly increases risk of developing lung disease
Meta-analysis of over 1 million people finds prior pulmonary TB associated with 2.65 times higher odds of COPD.
A history of pulmonary tuberculosis is linked to a much higher risk of developing chronic obstructive pulmonary disease, especially in certa…
Individualized blood pressure management reduces delirium but does not impact acute kidney injury or mortality
Individualized Blood Pressure Care Cuts Delirium Risk
This meta-analysis of 4,017 adults undergoing major non-cardiac surgery found that individualized blood pressure management significantly re…
Tailoring blood pressure during surgery may lower delirium risk, but doesn't reduce kidney injury or death, new analysis finds.
Obstructive sleep apnea syndrome is associated with significantly higher blood pressure variability in patients
Sleep apnea is linked to higher blood pressure variability
This meta-analysis of 17 datasets involving 2,087 total participants found that individuals with obstructive sleep apnea syndrome (OSAS) exh…
People with obstructive sleep apnea show significantly more blood pressure fluctuations during the night and day compared to those without t…
Integrated TCM and Western medicine increases pregnancy rate and ovulation rates in PCOS-related infertility
Combining Chinese and Western medicine may help PCOS infertility
This umbrella meta-analysis evaluates integrated traditional Chinese medicine (TCM) and Western medicine for women with PCOS-related inferti…
Combining traditional Chinese medicine with western treatments shows promise for improving ovulation and pregnancy rates in women with PCOS.
Most children with congenital myopathies maintain preserved intellectual functioning despite varying neuropsychological profiles
Children with Congenital Myopathies Often Maintain Intellectual Functioning
This systematic review examines cognitive development, neuropsychological outcomes, and quality of life in pediatric patients with various c…
Most children with congenital myopathies maintain their intellectual abilities, though specific conditions like ACTA1 may involve more sever…
Glucocorticoid signaling and stress-related neuroendocrine dysregulation influence intraocular pressure and inflammatory pathways in ocular diseases
Stress and hormones may play a role in eye health
This narrative literature overview of 35 studies synthesizes the role of glucocorticoid signaling and stress-related neuroendocrine dysregul…
New research suggests that stress-related hormone changes could influence conditions like glaucoma and other serious eye diseases.
Viral mimicry induction via epigenetic therapies and DNA damage may convert cold tumors to hot
New Strategies May Help Overcome Cancer Treatment Resistance
This narrative review explores strategies to overcome immune checkpoint blockade resistance in solid tumors. The authors suggest that induci…
Scientists are exploring ways to turn "cold" tumors into "hot" ones to help patients whose cancer is no longer responding to immunotherapy.
FDA Approves Bonsity (teriparatide) for Osteoporosis Treatment
FDA approves new osteoporosis drug Bonsity for high-risk patients
The FDA has approved Bonsity (teriparatide) for the treatment of osteoporosis in postmenopausal women, men with primary or hypogonadal osteo…
The FDA has approved Bonsity (teriparatide) to treat osteoporosis in people at high risk for fractures. It is for postmenopausal women, men …