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Phase 3 Completed N=156 Randomized Quadruple-blind Treatment

Treatments for Depression: Drug Versus Psychotherapy

Source: ClinicalTrials.gov NCT00043550 ↗
Enrolled (actual)
156
Serious AEs
0.0%
Results posted
Jun 2017
Primary outcomePrimary: Hamilton Rating Scale for Depression-17 Item — 19.0; 19.9; 19.4; 13.9 units on a scale — p=.95

Summary

This 4-8 month study, with a 2-year follow up period, will compare sertraline (Zoloft®), venlafaxine (Effexor®), supportive-expressive psychotherapy, and placebo to determine which is more effective in treating major depression.

Outcome Measures

OutcomeResultp-value
PRIMARY
Hamilton Rating Scale for Depression-17 Item
19.0; 19.9; 19.4; 13.9; 12.5; 12.7 .95

Eligibility Criteria

Inclusion criteria

  • Major Depressive Disorder diagnosis

Exclusion criteria

  • Psychotic or bipolar disorder diagnosis
  • Substance dependence in the last 6 months
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00043550). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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