N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 Testing TRUST Depression Management Intervention
Depressive Symptoms · Quality of Life
Primary: Patient Health Questionnaire-8 Adolescent — 6.17; 9.43; 6.80; 8.29 units on a scale
N/A N=64 Virtual Reality Compared to Screen Based Engagement on Mood
Virtual Reality
Primary: Change in Positive Affect and Negative Affect From Baseline to After a 2 Minute Mood Induction — 3.7; 4.63; 1.97; 1.56 units on a scale
N/A N=201 Depression Outpatient Cardiology Screening Study
Depression · Coronary Heart Disease
Primary: Beck Depression Inventory 2 — 17.4; 15.9 units on a scale
N/A N=1,001 The Effects of Videogames on Depression Symptoms and Brain Dynamics
Major Depressive Disorder
Primary: PHQ-9 Total Change From Baseline to Posttreatment: Experimental Group vs. Treatment as Usual Group — -1.941; -0.803 adjusted score change — p=0.0000022
Phase 3 N=131 Depression in Alzheimer's Disease-2
Alzheimer's Disease · Depression
Primary: Modfied Alzheimer's Disease Cooperative Study- Clinical Global Impression of Change (mADCS-CGIC) — 1; 0; 5; 2 participants — p=0.98
Phase 4 N=40 Depression, Epinephrine, and Platelet Function
Major Depressive Disorder
Primary: Response of Participants, Defined by Change in the 21-item Hamilton Depression Rating Scale (HDRS) From Baseline to Week8 — 5; 9; 2; 4 participants — p=.918
Phase 2 N=902 An Expert System to Reduce Depression in Primary Care
Depression · Depressive Disorder, Major
Primary: Change in Depression Severity — -5.4; -3.7 units on a scale — p=.003
Phase 4 N=16 Identifying and Treating Depression in Hemodialysis Patients
Depression · Hemodialysis-Induced Symptom
Primary: To Determine the Impact of Directly Observed Weekly Fluoxetine Treatment on Remission of Depression Among Hemodialysis Patients. — 6.6 units on a scale
N/A N=48 Group Depression Treatment for Autistic Youth
Autism Spectrum Disorder · Depression · Suicidal Ideation
Primary: Change in Severity of Adolescent Depressive Symptoms, Self-report — 8.14 T-score
N/A N=8 Wake Therapy in the Treatment of Depression
Major Depressive Disorder · Bipolar Disorder
Primary: Structured Interview for the Hamilton Depression Scale With Atypical Depression Supplement(SIGH-ADS) — 16.6 score on a scale
N/A N=1,460 A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Depression Trial)
Depression
Primary: Change in Depression Symptom Control as Measured by PROMIS (Patient-Reported Outcomes Measurement Information System) — -4.3; -4.0 T-score — p=0.677
N/A N=57 Improving Depression Management
Depression
Primary: Patient Health Questionnaire (PHQ-9) — 12.6; 15.2 score on a scale
N/A N=9 European Deep Brain Stimulation (DBS) Depression Study
Depressive Disorder, Major
Primary: Mean Percent Change From Baseline in MADRS Score — -7.7; -7.4; -8.8; -6.2 percentage change from baseline
N/A N=26 Transcranial Direct Current Stimulation Therapy for Major Depression
Major Depressive Disorder
Primary: Clinical Response — 22 Participants
N/A N=84 Spirituality Teaching Program for Depressed Adults
Major Depression
Primary: Hamilton Depression Rating Scale - Depression Severity — 20.4; 20.3; 11.9; 18.0 units on a scale
Phase 4 N=59 Desvenlafaxine vs. Placebo Treatment of Chronic Depression
Dysthymic Disorder · Dysthymia · Chronic Depressive Disorder
Primary: Hamilton Rating Scale for Depression (HDRS24) — 14.63; 14.21 units on a scale — p=0.09
N/A N=60 A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19
Depression
Primary: Phase I - Feasibility (Eligibility) — 35; 25 Participants
N/A N=80 Coping With Depression in Parkinson's Disease
Parkinson's Disease · Depression
Primary: Hamilton Depression Rating Scale: Baseline — 20.93; 19.38 units on a scale
N/A N=200 Depression and Anxiety in Rheumatoid Arthritis
Rheumatoid Arthritis · Depression · Anxiety
Primary: Hospital Anxiety and Depression Scale (HADS) — 107; 46; 20; 27 participants
N/A N=73 Drug Therapy to Treat Minor Depression
Depression
Primary: Efficacy Assessed Using the Inventory of Depressive Symptomatology - Clinician Rated (IDS-C) — -11.47; -9.35; -10.49 units on a scale
Phase 4 N=65 Duloxetine for Chronic Depression: a Double-blind Study
Dysthymic Disorder · Depressive Disorder NOS
Primary: Hamilton Depression Rating Scale (HDRS) - 24 Total Score — 5; 10 Scores on a scale — p=.003
N/A N=33 Mindfulness Intervention to Study the Neurobiology of Depression
Depression
Primary: Change in Children's Depression Rating Scale - Revised — 27.47; 28.00; 25.53; 31.86 units on a scale
N/A N=15 Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression
Depression
Primary: Skills of Cognitive Therapy (Patient Version) — 24.231; 24.231 units on a scale
Phase 2 N=12 Pramipexole to Target "Anhedonic Depression"
Depression, Bipolar · Depression, Unipolar · Dysthymia
Primary: Dimensional Anhedonia Rating Scale (DARS) Score — 15.75; 33.08 score on a scale
Phase 4 N=95 Stress and Inflammation in Late-Life Depression
Depression · Inflammation
Primary: IL-6 Levels — 5.25; 18.24; 3.69; 6.84 pg/mL — p=.44
Early Phase 1 N=39 Defining and Treating Depression-related Asthma
Asthma · Depression · Childhood Asthma
Primary: FEV1 Percent Change Post-ipratropium — 10.8 percent change — p=0.032
N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
N/A N=141 Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients
Pulmonary Disease, Chronic Obstructive · Major Depression
Primary: Composite Antidepressant Score Scale (CAD) — 29; 25; 9; 20 Participants
N/A N=30 Treatments for Improving Mood in Depressed Teens-3
Depression
Primary: Acceptability — 11; 13 Participants