N/A
N=94
Medication Treatment for Depression in Nursing Home Residents
Depression
Bottom Line
View on ClinicalTrials.gov: NCT00076622 ↗Enrolled (actual)
94
Serious AEs
33.0%
Results posted
Jan 2018
Primary outcome: Primary: Geriatric Depression Scale (GDS) Score — 5.11; 5.03; 4.59; 4.64 units on a scale
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Antidepressant medication (Drug); No antidepressant medication (Drug)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- University of Pennsylvania
- Primary completion
- Jul 2009
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Geriatric Depression Scale (GDS) Score |
5.11; 5.03; 4.59; 4.64 | — |
| PRIMARY Number of Falls Experienced by Participants Over Twelve Months of Surveillance |
12; 9; 26; 10 | — |
| SECONDARY Cognitive Function (MMSE) |
23.1; 24.9; 24.4; 24.3 | — |
Summary
This study will examine therapeutic and adverse effects of continuing versus discontinuing antidepressant medication in nursing home residents who have had no more than a single episode of depression and who no longer have depressive symptoms.
Eligibility Criteria
Inclusion Criteria
- Current use of antidepressant medication
- Have been in remission from first episode of depression for 6 months or longer
- Currently residing in a long term care or assisted living facility
Exclusion Criteria
- Bedridden
- Severe cognitive impairment
Data sourced from ClinicalTrials.gov (NCT00076622). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.