Phase 3 N=38 Randomized Single-blind Treatment

Motivational Interviewing to Improve Work Outcomes in Schizophrenia

Schizoaffective Disorder · Schizophrenia

Bottom Line

View on ClinicalTrials.gov: NCT00261716 ↗

Enrolled (actual)

Serious AEs

29.0%

Results posted

Aug 2016

Primary outcome: Primary: Obtained Employment — 7; 12; 10; 9 participants — p=.33

Study Design & Population

Study type: Interventional
Phase: Phase 3
Interventions: IPS (Behavioral); IE (Behavioral); VOMI (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: VA Office of Research and Development
Primary completion: Sep 2008

Outcome Measures

Outcome	Result	p-value
PRIMARY Obtained Employment	7; 12; 10; 9	.33
PRIMARY Average Number of Days Worked	93.47; 110	.75
PRIMARY Average Number of Hours Worked Per Week For Those Who Worked	18.24; 13.10	.41
SECONDARY Obtained a Second Job if Lost First Job and Still Had at Least 2 Months in the Program	3; 8; 2; 2	>.05
SECONDARY Association Between Employment Status and Psychiatric Symptoms as Measured on the Brief Psychiatric Rating Scale	39.88; 42.20; 41.17; 41.92; 39.63; 37.75	.37
SECONDARY Association Between Employment Status and Self-reported Life Satisfaction Measured on the Quality of Life Scale (Lehman)	5.00; 5.11; 5.50; 4.69; 5.0; 5.44	.62
SECONDARY Association Between Employment Status and Overall Adjustment as Rated on the Social Adjustment Scale II (Schooler)	3.63; 4.29; 3.75; 4.17; 3.13; 4.0	.19

Summary

Many persons with schizophrenia have difficulty getting and keeping a job. This study is designed to compare the benefits of four sessions of motivational interviewing or illness education in increasing employment rates accruing from participation in supported employment.

Eligibility Criteria

Inclusion Criteria

Patient must have schizophrenia or schizoaffective disease
Currently unemployed but want to get at least a part time job
Be on a stable medication regimen and compliant with treatment
Live within one hour of the hospital
Be willing to have care transferred to the Schizophrenia Outpatient Clinic at VA Greater Los Angeles Healthcare System

Exclusion Criteria

Organic brain disease
Physical illnesses that would preclude working

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00261716). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.