Phase 2
N=9
Research Study of Treatment for Winter Depression With Different Colors of Light
Seasonal Affective Disorder
Bottom Line
View on ClinicalTrials.gov: NCT00269633 ↗Enrolled (actual)
9
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcome: Primary: Structured Interview Guide for the Hamilton Depression Scale - Seasonal Affective Disorder Version (SIGH-SAD); Weekly for Three Weeks — 16.3; 8 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- Blue Light Box 467 nm (Device); Red Light Box 657 nm (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Thomas Jefferson University
- Primary completion
- May 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Structured Interview Guide for the Hamilton Depression Scale - Seasonal Affective Disorder Version (SIGH-SAD); Weekly for Three Weeks |
16.3; 8 | — |
Summary
The specific aim of this study is to test the hypothesis that light stimuli concentrated around 467 nm will evoke a significantly stronger therapeutic response in SAD patients compared to light stimuli concentrated around 657 nm at an equal photon density.
The secondary objective of this study is to determine the efficacy of different colors and levels of light in order to optimize therapeutic benefit, while also minimizing side effects and maintaining safety of light exposure.
Eligibility Criteria
Inclusion Criteria
- Clinical diagnosis of Seasonal Affective Disorder
- Over 18 years old
- Stable sleeping pattern with a bedtime no later than 1 a.m.
Exclusion Criteria
- Pregnant women
- Concurrent psychiatric illness that would preclude compliance with the protocol
- active suicidal or homicidal ideation or plan
- variable psychiatric illness (i.e. rapid cycling disorder or severe premenstrual syndrome)
- individuals with substance abuse or dependence who have not been in remission for at least one year
- individuals taking photosensitizing medications
- individuals with macular degeneration or other ocular conditions which might be adversely affected by light
- less then six weeks after onset of psychotherapeutic treatment
Data sourced from ClinicalTrials.gov (NCT00269633). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.