Clinical Trial Search

Primary: Percentage SIGH SAD (Structured Interview Guide For The Hamilton Depression Rating Scale), SAD Version — 34.5; 60.4 Percentage of SIGH SAD — p=0.028

Primary: Scores on the Structured Interview Guide for the Hamilton Depression Rating Scale-Seasonal Affective Disorder Version — 13.6; 13.3; 8.3; 22.6 units on a scale

Primary: Percentage Change SIGH SAD Depression Rating — -36.4; -52.7 percentage of change on SIGH SAD — p=0.014

Primary: Sleep Satisfaction at Baseline and Measured Monthly, as Measured by the Pittsburgh Sleep Quality Index (PSQI) — 11.56; 11.45; 9.52; 8.67 scores on a scale

Primary: SIGH-ADS Score — 29.4; 25.8; 5.6; 4.5 units on a scale — p=0.74

Primary: Structured Interview Guide for the Hamilton Depression Scale - Seasonal Affective Disorder Version (SIGH-SAD); Weekly for Three Weeks — 16.3; 8 units on a scale

Primary: Structured Interview for the Hamilton Depression Scale With Atypical Depression Supplement(SIGH-ADS) — 16.6 score on a scale

Primary: Change From Baseline Score of the Hamilton Depression Rating Scale-Seasonal Affective Version (SIGH-SAD) at 5 Weeks — 24.75; 12.88 SIGH-SAD score — p=.001

Primary: 17-Item Hamilton Rating Scale for Depression Score (Independent Evaluator) — 8.66; 10.46 units on a scale

Primary: Pittsburgh Sleep Quality Index — 7.0 units on a scale — p=0.37

Primary: Total Score on the Hamilton Rating Score for Depression (HRSD) - 21 Item Version — 19; 18.5; 10.2; 14.4 Total score on a scale — p=<0.05

Primary: Length of Hospitalization — 11 days

Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001

Primary: Mean Difference of Systolic Daytime Ambulatory Blood Pressure Between Summer and Winter. — 7.7 mmHg

Primary: Change in the Montgomery-Asberg Depression Rating Scale (MADRS) Score — -13.60; -8.82; -8.27 units on a scale — p=>0.10

Primary: Change From Baseline to Endpoint at Week 8 Using the Total Score of the Hamilton Depression Rating Scale (HAM-D) — -8.19; -7.83; -13.6 units on a scale

Primary: SIGH-ADS Depression Score — 10.3; 17.3 units on a scale — p==0.005

Primary: Severity of Depression as Measured by the Quick Inventory of Depressive Symptomatology (QIDS) Pre-Treatment — 10.8; 10.8 score on a scale

Primary: Bedtime — 7.44; 7.24; 22.98; 22.48 Hours

Primary: Change in PTSD Checklist for DSM-5 (PCL-5) Scores Over 4 Weeks of Treatment — 15.11; 2.50 units on a scale

Primary: Visual Analogue Scale for Anxiety Symptoms (VAS-anxiety) — 12.1; 19.6 units on a scale

Primary: Montgomery-Asberg Depression Scale (MADRS) — 29.4; 28.3; 24.7; 24.2 units on a scale — p=1.0

Primary: Hamilton Depression Rating Scale Remission Rates — 46.1; 17.6 Percentage of Remitters HDRS17

Primary: Change in Average Fatigue Severity Scale (FSS) Score — 45.824; 46.714 score on a scale

Primary: Positive Affect Subscale of the Positive and Negative Affect Scale (PANAS-P) — 20.76; 29.42; 24.18; 19.42 score on a scale — p=.002

Primary: Hamilton Rating Scale for Depression (HRSD) — 12.32; 12.06; 20.20; 20.08 units on a scale — p=.016

Primary: Change in Depressive Symptoms — 1.6; 2.2 units on a scale

Primary: Fatigue — 15.25; 21.6 units on a scale

Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale

Primary: Total Sleep Time — 393; 420; 398; 409 units on a scale (minutes)