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Home › Conditions › seasonal affective disorder

Seasonal affective disorder

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for seasonal affective disorder

6 trials tracked for seasonal affective disorder: 2 in phase 3 or 4.

6Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 1 Phase 2 1 Phase 1 1 Other / NA 2
  1. Phase 4 Ramelteon in the Treatment of Sleep and Mood in Patients With Seasonal Affective Disorder Completed
  2. Phase 3 A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD) Completed
  3. Phase 2 Research Study of Treatment for Winter Depression With Different Colors of Light Completed
  4. Phase 1 Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD) Completed
  5. N/A Environmental Treatment for Seasonal Affective Disorder (SAD) Completed
  6. N/A 30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
No significant seasonal variation in brain SERT availability found in paired longitudinal studies
Radiology & Imaging Meta-analysis
No significant seasonal variation in brain SERT availability found in paired longitudinal studies Brain chemistry changes may explain seasonal sadness and mood shifts
This meta-analysis examined seasonal variation in brain SERT availability in healthy human subjects. The analysis found no significant seaso…
New data suggests that specific brain protein changes in winter might be a personal risk factor for seasonal mood disorders.
Oct 15, 2026
Observational Study Links Latitude and Genetics to Seasonal Affective Disorder Risk in Adults
Genetics & Precision Medicine
Observational Study Links Latitude and Genetics to Seasonal Affective Disorder Risk in Adults Winter Blues Tied to Genes and Where You Live
This primary research article analyzes data from 12,460 adults in the Australian Genetics of Depression Study.
Where you live and the genes you carry may shape how much winter drags down your mood — and it’s not just about sunlight.
medRxiv Apr 24, 2026