Translating the DPP Into the Community
Prediabetic State · Overweight · Obesity
Bottom Line
View on ClinicalTrials.gov: NCT00302042 ↗Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Brief counseling plus group diabetes prevention in community (Behavioral); Brief Counseling for pre-diabetes alone (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Northwestern University
- Primary completion
- Aug 2007
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Weight |
-6.0; -2.0 | — |
| SECONDARY Physical Activity Level |
— | — |
| SECONDARY Rate of Community Program Participation |
— | — |
| SECONDARY Change in Dietary Composition |
— | — |
Summary
Eligibility Criteria
Inclusion Criteria
i. 18 years of age or older ii. Body-mass index of >= 24 kg/m2 iii. ADA diabetes risk assessment score >= 10 (see below) iv. Casual capillary blood glucose >= 110 mg/dl
Exclusion Criteria
i. Exclusions for diseases likely to limit life span and/or increase risk of interventions:
A. Cancer requiring treatment in the past 5 years
B. Cardiovascular disease:
- A "Yes" response to any item on the modified Physical Activity Readiness Questionnaire (see Appendix 2)
- Uncontrolled hypertension: systolic blood pressure >180 mmHg or diastolic blood pressure >105 mmHg
- Heart attack, stroke, or transient ischemic attack in the past 6 months, C. Lung disease: Chronic obstructive airways disease or asthma requiring home oxygen
ii. Exclusions related to metabolism: A. Diabetes at baseline evaluation B. Casual capillary blood glucose >= 200 mg/dl C. History of anti-diabetic medication use (oral agents or insulin) except during gestational diabetes
D. Pregnant female E. Self-report of disease associated with disordered glucose metabolism: Cushing's syndrome; acromegaly; pheochromocytoma; chronic pancreatitis
iii. Exclusion for conditions or behaviors likely to affect the conduct of the study:
A. Unable or unwilling to provide informed consent B. Unable to communicate with the pertinent clinic staff C. Unable to read written English
Data sourced from ClinicalTrials.gov (NCT00302042). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.