Phase 3
Completed N=201
Comparison of Psychotherapy Programs to Treat Panic Disorder
Source: ClinicalTrials.gov NCT00353470 ↗Enrolled (actual)
201
Serious AEs
1.0%
Results posted
Dec 2022
Primary outcomePrimary: Panic Disorder Severity Scale — 6.72; 5.78; 7 score on a scale — p=>0.16
◆ Published Evidence
Established
82citations · ~8 / year
Psychotherapies for Panic Disorder: A Tale of Two Sites.
Summary
This study will determine the relative effectiveness of three psychotherapies in treating people with a panic disorder.
Linked Publications (5)
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Psychotherapies for Panic Disorder: A Tale of Two Sites.
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Processes of therapeutic change: Results from the Cornell-Penn Study of Psychotherapies for Panic Disorder.
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Predictors and moderators of treatment dropout in cognitive-behavioral and psychodynamic therapies for panic disorder.
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In-session emotional expression predicts symptomatic and panic-specific reflective functioning improvements in panic-focused psychodynamic psychotherapy.
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Differential effects of alliance and techniques on Panic-Specific Reflective Function and misinterpretation of bodily sensations in two treatments for panic.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Panic Disorder Severity Scale |
6.72; 5.78; 7 | >0.16 |
| SECONDARY Sheehan Disability Scale |
6.4; 6.28; 6.9 | — |
| SECONDARY Clinical Global Impressions Scale |
2.17; 2.16; 2.38 | — |
| SECONDARY Hamilton Depression Rating Scale |
11.37; 10.18; 11.55 | — |
| SECONDARY Hamilton Anxiety Rating Scale |
7.97; 7.87; 6.30 | — |
| SECONDARY Anxiety Disorder Sensitivity Index |
27.07; 17.71; 19.09 | — |
| SECONDARY Brief Body Sensitivity Interpretation Questionnaire (BBSIQ) |
1.80; 1.62; 1.70 | — |
| SECONDARY Panic-Specific Reflective Function |
4.67; 3.67; 3.20 | — |
Eligibility Criteria
Inclusion Criteria
- Meets DSM-IV diagnosis criteria for primary PD with or without agoraphobia
- History of at least one spontaneous panic attack per week within the month prior to study entry
Exclusion Criteria
- Active substance dependence within 6 months prior to study entry
- Lifetime history of any psychotic disorder, including bipolar disorder
- Acutely suicidal
Data sourced from ClinicalTrials.gov (NCT00353470) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.