Phase 3
N=201
Comparison of Psychotherapy Programs to Treat Panic Disorder
Anxiety Disorders · Panic Disorder · Agoraphobia
Bottom Line
View on ClinicalTrials.gov: NCT00353470 ↗Enrolled (actual)
201
Serious AEs
1.0%
Results posted
Dec 2022
Primary outcome: Primary: Panic Disorder Severity Scale — 6.72; 5.78; 7 score on a scale — p=>0.16
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- Cognitive behavioral therapy (Behavioral); Applied relaxation training (ART) (Behavioral); Panic focused psychodynamic psychotherapy (PFPP) (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Weill Medical College of Cornell University
- Primary completion
- Mar 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Panic Disorder Severity Scale |
6.72; 5.78; 7 | >0.16 |
| SECONDARY Sheehan Disability Scale |
6.4; 6.28; 6.9 | — |
| SECONDARY Clinical Global Impressions Scale |
2.17; 2.16; 2.38 | — |
| SECONDARY Hamilton Depression Rating Scale |
11.37; 10.18; 11.55 | — |
| SECONDARY Hamilton Anxiety Rating Scale |
7.97; 7.87; 6.30 | — |
| SECONDARY Anxiety Disorder Sensitivity Index |
27.07; 17.71; 19.09 | — |
| SECONDARY Brief Body Sensitivity Interpretation Questionnaire (BBSIQ) |
1.80; 1.62; 1.70 | — |
| SECONDARY Panic-Specific Reflective Function |
4.67; 3.67; 3.20 | — |
Summary
This study will determine the relative effectiveness of three psychotherapies in treating people with a panic disorder.
Eligibility Criteria
Inclusion Criteria
- Meets DSM-IV diagnosis criteria for primary PD with or without agoraphobia
- History of at least one spontaneous panic attack per week within the month prior to study entry
Exclusion Criteria
- Active substance dependence within 6 months prior to study entry
- Lifetime history of any psychotic disorder, including bipolar disorder
- Acutely suicidal
Data sourced from ClinicalTrials.gov (NCT00353470). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.