N/A
N=338
Vascular Risk After Kidney Transplantation
Cardiovascular Disease · Chronic Kidney Disease · Diabetes · Vitamin D Deficiency · Hyperparathyroidism
Bottom Line
View on ClinicalTrials.gov: NCT00374595 ↗Enrolled (actual)
338
Serious AEs
0.0%
Results posted
Aug 2023
Primary outcome: Primary: Carotid Intima Media Thickness (CIMT) — 0.044 millimeters (mm)
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 19+ yrs
- Sex
- All
- Sponsor
- University of Nebraska
- Primary completion
- Jul 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Carotid Intima Media Thickness (CIMT) |
0.044 | — |
Summary
Hypothesis: Nontraditional risk factors, such as inflammation, vitamin D deficiency, elevated PTH, insulin resistance, homocysteine, or uric acid, contribute to cardiovascular disease progression after kidney transplant.
The purpose of this study is to evaluate which traditional and nontraditional cardiovascular disease risk factors best predict progression of cardiovascular disease (CVD) using carotid intima media thickness performed by ultrasound, in kidney transplant patients.
Eligibility Criteria
Inclusion Criteria
- Kidney transplant more than 6 months ago
- 19 years or older
Exclusion Criteria
- Estimated GFR <30
- Previous small bowel, or lung transplant
- Pancreas transplant less than 6 months ago
- Cancer or any condition that would change weight dramatically in the near future such as malabsorption.
- Willing to return for testing annually for 3 years
- Women who are pregnant
Data sourced from ClinicalTrials.gov (NCT00374595). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.