Phase 1 N=12 Treatment

Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury

Depression · Self-injurious Behavior

Bottom Line

View on ClinicalTrials.gov: NCT00401102 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2013

Primary outcome: Primary: CGI

Study Design & Population

Study type: Interventional
Phase: Phase 1
Interventions: Interpersonal Psychotherapy for Depressed Adolescents (Behavioral)
Age: Pediatric, Adult · 12+ yrs
Sex: All
Sponsor: New York State Psychiatric Institute
Primary completion: Sep 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY CGI	—	—
PRIMARY C-GAS	—	—
PRIMARY CDRS	—	—
PRIMARY Self-Injurious Thoughts and Behaviors Interview	0.4	—
PRIMARY Self-injury Monitoring Card	—	—
SECONDARY Beck Depression Inventory	—	—
SECONDARY Multidimensional Anxiety Scale for Children	—	—

Summary

The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of depression and are engaging in non-suicidal self-injurious behaviors. The trial will include recruiting 10 particpants, administering 12-sessions of individual IPT-A, and determining how the IPT-A protocol needs to be amended to adequately address the self-injury in addition to depression.

Eligibility Criteria

Inclusion Criteria

12 to 18 years of age
Diagnosis of MDD, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder with depressed Mood
Non-suicidal self-injurious behavior
CDRS >= 36
C-GAS <= 65
English speaking patient
One English speaking caregiver -

Exclusion Criteria

Suicide attempt within past 6 months or actively suicidal
Severe incident of non-suicidal self-injury in past 3 months
Severe episode of MDD
Treatment resistant non-suicidal self-injury
Frequent non-suicidal self-injury
Mentally retarded
Current diagnosis of: PTSD, OCD, Schizophrenia, Bipolar Disorder, Psychosis, Substance Dependence, ADHD
Current substance use
Currently in active treatment for same condition
Currently taking antidepressant medication
Medical illness likely to interfere with treatment -

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00401102). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.