Phase 3
Completed N=325
Effectiveness of Telephone Versus Face-to-Face CBT in Treating People With Depression
Source: ClinicalTrials.gov NCT00498706 ↗Enrolled (actual)
325
Serious AEs
0.0%
Results posted
Jul 2013
Primary outcomePrimary: Attrition (Number of Therapy Sessions Attended) — 15.4; 13.7 Number of Sessions — p=0.003
Summary
This study will compare the effectiveness of telephone versus face-to-face administration of cognitive behavioral therapy in treating people with depression.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Attrition (Number of Therapy Sessions Attended) |
15.4; 13.7 | 0.003 sig |
| PRIMARY Number of Participants Who Dropped Out of Therapy |
34; 53; 7; 21 | 0.02 sig |
| PRIMARY Patient Health Questionnaire (PHQ)-9 |
16.76; 16.76; 10.78; 10.09; 9.05; 8.62 | 0.89 |
| PRIMARY Depression, as Assessed by Hamilton Depression Rating Scale(Ham-D) |
22.83; 22.83; 18.07; 17.86; 15.62; 16.45 | 0.22 |
| SECONDARY Health-related Quality of Life (SF-36V), Patient Satisfaction (Satisfaction Index - Mental Health), and Therapeutic Alliance (Working Alliance Inventory - Short Form) |
— | — |
Eligibility Criteria
Inclusion Criteria
- Has a current diagnosis of major depressive disorder
- Has a primary care physician at Northwestern University in Illinois, or one of a number of approved community clinics in Chicago.
- Resides in Illinois
- Has a telephone
- Speaks and reads English
Exclusion Criteria
- Hearing, voice, or visual impairment
- Meets criteria for dementia
- Diagnosed with a psychotic disorder, bipolar disorder, dissociative disorder, current substance abuse, or other condition for which participation in a clinical trial of psychotherapy may be either inappropriate or dangerous
- Currently receiving individual psychotherapy or planning to receive psychotherapy during the treatment phase of the study
- Planning to be out of town or unavailable for treatment for 4 weeks or more during the scheduled treatment time
- Recent history of suicide attempts or is severely suicidal
- Initiated treatment with an antidepressant in the 2 months before study entry (antidepressant medication is not exclusionary)
- Depression determined to be primarily of an organic etiology
Data sourced from ClinicalTrials.gov (NCT00498706). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.