N/A Completed N=36 Diagnostic

Exercise,Metabolic Syndrome and Weight Regain (Echocardiography Substudy)

Metabolic Syndrome · Obesity

Source: ClinicalTrials.gov NCT00543985 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2016

Primary outcomePrimary: Mean Resting E/E' — 7.01 ml/min/kg — p==0.14

Summary

We plan to test the hypothesis that patients with metabolic syndrome will have impaired left ventricular diastolic parameters. These parameters will be measured before and after a stress test at the end of a 3 month period of exercise training and a 10% weight loss.

Outcome Measures

Outcome	Result	p-value
PRIMARY Mean Resting E/E'	7.01	=0.14
PRIMARY Post-exercise E/E'	7.41	—
SECONDARY Mean Resting Maximal Oxygen Uptake (VO2 Max)	—	—
SECONDARY Change in Maximal Oxygen Uptake (VO2 Max)	—	—

Eligibility Criteria

Inclusion Criteria

2 of 5 criteria for metabolic syndrome
Ability to exercise for 45 min 5 days a week

Exclusion Criteria

No diabetes
Established coronary disease

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00543985). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.