Phase 4
Completed N=510
Comparative Performance of PureVision, Acuvue Oasys and O2Optix
Source: ClinicalTrials.gov NCT00640341 ↗Enrolled (actual)
510
Serious AEs
0.0%
Results posted
Mar 2011
Primary outcomePrimary: Any Slit Lamp Finding > Grade 2 — 2; 5; 10 Eyes
Summary
The objective of this study is to evaluate the performance of the PureVision Contact Lens compared to Acuvue Oasys Contact lens and O2Optix Contact lens when worn on a daily wear basis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Any Slit Lamp Finding > Grade 2 |
2; 5; 10 | — |
| PRIMARY Subjective Responses to Comfort-related Symptoms/Complaints |
85.5; 92.9; 92.0; 82.9; 90.1; 88.4 | — |
| PRIMARY Uncorrected Distance High Contrast Visual Acuity |
-0.031; -0.026; -0.024 | — |
Eligibility Criteria
Inclusion Criteria
- Subject is myopic
- VA correctable to 0.3 LogMAR or better (driving vision)
- Clear central cornea
- Subject uses a lens care system on a regular basis
Exclusion Criteria
- Systemic disease affecting ocular health
- Using systemic or topical medications
- Wear monovision, multifocal or toric contact lenses
- Any grade 2 or greater slit lamp findings
Data sourced from ClinicalTrials.gov (NCT00640341). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.