Phase 2 N=97 Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia
Primary: Axial Length at 36 Months — 25.28; 25.25; 25.33 mm
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=86 Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
Myopia · Esophoria · Fixation Disparity
Primary: Changes in Cycloplegic Autorefraction in One Year. — -0.22; -0.78 Diopters
Phase 3 N=118 Correction of Myopia Evaluation Trial 2
Myopia
Primary: Distribution of Change in Spherical Equivalent Refractive Error From Baseline to 3 Years — 6; 3; 11; 8 participants
N/A N=100 Myopia Assessment of Two Manufacturing Processes
Juvenile Myopia
Primary: Change in Axial Length Progression From Baseline — 0.046; 0.047 mm
N/A N=183 Myopia Control With the Multi-segment Lens
Myopia
Primary: Cycloplegic Refraction Change in SER — -0.93; -0.38 Diopters (D)
N/A N=100 Evaluation of a Night Spectacle Correction Concerning an Improvement of Mesopic Vision Quality
Myopia-Night Blindness
Primary: Night Myopia — -0.30; -0.32 D
N/A N=152 Controlling Myopia Progression With Soft Contact Lenses
Myopia
Primary: Axial Length (Axial Elongation) — 0.158; 0.144; 0.121; 0.242 millimeter (mm)
N/A N=92 Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Myopia
Primary: Axial Lenght Increase — 0.27; 0.37 mm
N/A N=137 Controlling Myopia Progression With Soft Contact Lenses
Myopia
Primary: Spherical Equivalent Refraction — -0.326; -0.460; -0.430; -0.898 diopter (D)
N/A N=114 VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
Myopia · Refractive Errors
Primary: Variability of the Refractive Predicatibility — -0.22 Diopters
N/A N=144 An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
Myopia
Primary: Change in Refractive Error Relative to Baseline — -0.18; -0.58 Diopters
N/A N=45 Effectiveness of Orthokeratology in Myopia Control
Myopia
Primary: Axial Length — 25.32; 26.08 mm
N/A N=127 Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
Myopia
Primary: Spherical Equivalent Refractive Error — -0.386; -0.185; -0.679; -0.548 diopter (D)
N/A N=248 Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control
Myopia
Primary: The Statistical Correlation Between Three-year Change in Choroidal Thickness and Three-year Change in Axial Length — 0.18 mm axial length — p=<0.001
N/A N=35 Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye
Cataract
Primary: Binocular Near Visual Acuity — 0.14 logMAR
N/A N=294 Bifocal Lenses In Nearsighted Kids
Refractive Errors
Primary: Refractive Error Progression — -3.46; -3.32; -2.84 Diopters — p=<0.01
N/A N=71 Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression Rate
Myopia
Primary: Annualized Changes in Refractive Error (SER) — -0.70; -0.66 Dioptre/year
N/A N=102 Retardation of Myopia in Orthokeratology
Myopia
Primary: Axial Elongation in the Study and Control Subjects Who Completed the Two Years Study — 0.36; 0.63 mm
N/A N=35 Enhancement of Emmetropization in Highly Hyperopic Infants
Hyperopia
Primary: Central Cycloplegic Refractive Error With Retinoscopy — 1.6; 1.2; 2.8 Diopters
N/A N=49 Bifocal & Atropine in Myopia (BAM) Study
Refractive Errors
Primary: Refractive Error Progression — -3.50 Diopter — p=0.70
Phase 3 N=200 A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
Choroidal Neovascularization Secondary to Pathologic Myopia
Primary: Number of Patients Treated and Re-treated Based on Presence/Absence of Active Leakage — 3; 0; 61; 121 Patients — p=<0.0001
N/A N=84 Accommodative Relief for Uncomfortable Non-Presbyopes
Asthenopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score — 14.3; 12.8; 19.0 scores on a scale — p=<0.001
N/A N=31 The Safety and Effectiveness of Breath-O Lenses
Myopia · Safety Issues
Primary: Corneal Biomechanics in Terms of Corneal Hysteresis and Resistance Factor — 11.12; 11.10; 10.37; 11.20 mmHg
Phase 3 N=187 Low-Dose Atropine for Treatment of Myopia
Myopia
Primary: Treatment Group Comparison of Change in Spherical Equivalent Refractive Error. — 0; 0; 1; 0 Participants
N/A N=82 Myopia Progression After Ceasing Myopia Control Contact Lens Wear
Myopia
Primary: Axial Length of the Eye — 0.080; 0.073; 0.229; 0.231 millimeter (mm)
N/A N=75 Visual Performance of Soft Contact Lenses With Myopia Control Optics
Visual Acuity
Primary: Binocular Visual Performance (LogMAR) — -0.10; -0.10; -0.07; -0.11 logMAR
N/A N=249 Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation
Hyperopia
Primary: Number of Participants With Confirmation of Failure Criteria — 5; 4; 11; 18 Participants — p=0.72
N/A N=21 Evaluation of The Clinical Acceptance of Soft Contact Lenses for Myopia Control
Myopia
Primary: Overall Vision Satisfaction — 87.7; 79.7; 71.8 units on a scale
Phase 3 N=457 Efficacy and Safety of Ranibizumab 0.5 vs Verteporfin PDT in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
Visual Impairment Due to Choroidal Neovascularization (CNV) Secondary to Pathologic Myopia (PM)
Primary: Change From Baseline BCVA to the Average Level of BCVA Over All Monthly Assessments From Month 1 to Month 3 — 53.7; 54.2; 52.6; 63.1 ETDRS letters — p=<0.001
N/A N=30 Marketed Contact Lens Real World Through Focus Curve
Visual Acuity
Primary: Distance Binocular LogMAR Visual Acuity — -1.072; -0.904; 0.9017; 0.557 -10*LogMAR