N/A
N=81
Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer
Skin Cancer · Basal Cell Carcinoma · Squamous Cell Carcinoma
Bottom Line
View on ClinicalTrials.gov: NCT00836342 ↗Enrolled (actual)
81
Serious AEs
0.0%
Results posted
Jul 2012
Primary outcome: Primary: Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Control Subjects — 27,635; 31,219 Raman spectroscopy intensity counts — p=0.31
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Massachusetts General Hospital
- Primary completion
- Jan 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Control Subjects |
27,635; 31,219 | 0.31 |
| SECONDARY Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Subjects With History of Basal Cell Carcinoma |
27,635; 25,031 | 0.49 |
| SECONDARY Skin Carotenoid Levels in Subjects With History of Basal Cell Carcinoma Versus Control Group |
25,031; 31,219 | 0.09 |
Summary
The purpose of this study is to determine the difference of skin carotenoid levels between subjects with previous squamous cell carcinomas (SCC), subjects with previous basal cell carcinomas (BCC) and a control group.
Eligibility Criteria
Inclusion Criteria
- Subjects between 50 and 75 years old without history of previous SCC or BCC.
- Fitzpatrick skin types I-IV.
- Willing and able to understand and sign informed consent.
- Able to complete study and comply with study procedures
Exclusion Criteria
- Regular ingestion of supplements containing carotenoids or vitamin A in the past 4 weeks.
- Use of topical retinoids in the past 4 weeks.
- Treatment with systemic retinoids in the past 6 months.
- Dermatologic conditions that require the use of interfering topical or systemic therapy or that might interfere with study assessments such as, but not limited to, palmar psoriasis, hand dermatitis or palmo-plantar keratoderma.
- Previous history of psoriasis.
- Clinically significant abnormal findings or conditions, which might, in the opinion of the Principal Investigator, interfere with study evaluations or pose a risk to subject safety during the study.
- Subjects who are known to be pregnant or planning a pregnancy.
Data sourced from ClinicalTrials.gov (NCT00836342). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.