Systematic review and meta-analysis on immunotherapy for head and neck squamous cell carcinoma
Immunotherapy helps advanced head and neck cancer patients live longer
This systematic review and meta-analysis synthesized evidence on immunotherapy for head and neck squamous cell carcinoma. The authors report…
New analysis shows immune therapy helps advanced head and neck cancer patients survive longer when combined with other treatments
FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
FDA approves subcutaneous nivolumab combination for multiple advanced cancers
This FDA approval document grants authorization for OPDIVO QVANTIG, a subcutaneous combination of nivolumab and hyaluronidase, for specified…
The FDA has approved a new subcutaneous form of nivolumab for several advanced cancers, offering a more convenient treatment option for elig…
Meta-analysis finds sex-based differences in ICI survival benefit for advanced gastroesophageal cancer
Immunotherapy Works Differently for Men and Women with Stomach Cancer
This meta-analysis of 15 RCTs examined immune-checkpoint inhibition for advanced gastroesophageal cancer. It found a significant overall sur…
Men with esophageal cancer gain a clear survival edge from immunotherapy, while women do not, but both sexes benefit similarly in stomach ca…
Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
New drug strategy targets mouth cancer's hidden power source
This narrative review discusses the potential of mitochondrial-targeted therapeutics in oral squamous cell carcinoma (OSCC). The authors syn…
Targeting the cell's power source could help overcome stubborn mouth cancer resistance.
Oropharyngeal cancer radiotherapy protocols show improved patient-reported outcomes over time
New treatments reduce pain and anxiety for throat cancer patients today
This combined RCT and observational study of 363 Swedish patients with oropharyngeal squamous cell carcinoma compared two treatment protocol…
New throat cancer treatments significantly reduce pain and anxiety while dry mouth persists for many patients
Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
A new cancer test reads tumor cell chats to predict survival
This meta-analysis of 2 cohorts (TCGA-HNSC n=519, GSE65858 n=270) found that the BCI_net directional composite was independently associated …
Your cancer cells may be chatting with each other, and a new test that listens to those conversations could predict how aggressive the disea…
Narrative review on therapeutic cancer vaccines for head and neck squamous cell carcinoma
Review discusses cancer vaccines for head and neck cancer
This narrative review synthesizes evidence on therapeutic cancer vaccines, including personalized vaccines, for head and neck squamous cell …
This review looks at how cancer vaccines might work alongside other treatments for head and neck squamous cell carcinoma.
Narrative review explores Veillonella's dynamic role in oral squamous cell carcinoma
Oral bacteria shift early in cancer and vanish as tumors grow
This narrative review examines the role of Veillonella species in oral squamous cell carcinoma (OSCC). The authors report a dynamic, stage-d…
A specific mouth bacteria appears early in cancer development but disappears as tumors grow larger, suggesting it helps start the problem ra…
Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
Cancer Patients Live Longer When Immunotherapy Starts Early in Day
This systematic review and meta-analysis evaluated 6129 patients with advanced solid tumors receiving immune checkpoint inhibitors. Earlier …
• Morning immunotherapy shots link to longer survival for advanced cancers • Helps patients fighting lung stomach kidney and other tough can…
Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
Adding radiation before surgery helps some esophageal cancer patients get better surgery results and live longer
This meta-analysis of 2,174 patients reveals that adding radiation to chemotherapy significantly boosts resection rates and survival for squ…
A large review found that adding radiation to chemotherapy before surgery helped remove more tumors in certain cancer types. This approach a…
Narrative review discusses HPV-associated head and neck and cervical squamous cell carcinoma without reporting specific outcomes
Doctors Find Hidden Pattern in HPV Cancers That Changes Treatment
This narrative review addresses patients with HPV-associated tumors involving head and neck squamous cell carcinoma and squamous cell carcin…
HPV cancers in the head and neck hide from the immune system differently than cervical cancers, explaining why some patients respond better …
GERD Associated with Increased Risk of Laryngeal Cancer in Meta-Analysis
Large study links GERD to higher risk of laryngeal cancer
A systematic review and meta-analysis of 1,768,394 adults found that gastroesophageal reflux disease (GERD) was significantly associated wit…
A massive analysis of nearly 1.8 million adults found a link between gastroesophageal reflux disease and increased risk of laryngeal cancer.
All Squamous Cell Carcinoma Articles
- Systematic review and meta-analysis on immunotherapy for head and neck squamous cell carcinoma
- FDA approves OPDIVO QVANTIG for multiple advanced cancer indications including renal cell carcinoma and melanoma
- Meta-analysis finds sex-based differences in ICI survival benefit for advanced gastroesophageal cancer
- Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
- Oropharyngeal cancer radiotherapy protocols show improved patient-reported outcomes over time
- Meta-analysis finds BCI_net prognostic for overall survival in oral squamous cell carcinoma
- Narrative review on therapeutic cancer vaccines for head and neck squamous cell carcinoma
- Narrative review explores Veillonella's dynamic role in oral squamous cell carcinoma
- Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
- Meta-analysis shows neoadjuvant chemoradiation improves resection and survival outcomes for esophageal squamous cell carcinoma patients compared to chemotherapy alone
- Narrative review discusses HPV-associated head and neck and cervical squamous cell carcinoma without reporting specific outcomes
- Review of multimodal deep learning model for esophageal squamous cell carcinoma diagnosis
- SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
- GERD Associated with Increased Risk of Laryngeal Cancer in Meta-Analysis
- Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
- Review of PBMC processing conditions in head and neck squamous cell carcinoma treatment-naive patients
- Narrative review discusses targeting ferroptosis and cuproptosis in oral squamous cell carcinoma
- Deep learning segmentation with CT elasticity features predicts right recurrent laryngeal nerve metastasis in esophageal cancer
- Iron and oxidative stress biomarkers linked to oral cancer recurrence after surgery
- Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
- Personalized swallowing rehab improves outcomes after oral cancer surgery
- High NSUN3 expression linked to poor survival in oral squamous cell carcinoma
- Becotatug vedotin shows 20.9% objective response in recurrent head and neck squamous cell carcinoma after prior therapy
- Classification framework shows 79% to 98% performance for oral squamous cell carcinoma on histopathological images
- Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
- Radiotherapy de-escalation strategies show reduced toxicity but modest clinical benefits in head and neck cancer cohorts
- Phase 1b ABBV-368 combinations in recurrent/metastatic HNSCC show 14.3% overall response rate
- Timing of surgery after neoadjuvant chemoimmunotherapy impacts survival in operable esophageal squamous cell carcinoma
- Phase 3 trial compares IMPT versus IMRT plus cisplatin in locally advanced oropharyngeal squamous cell carcinoma
- Low OT-NLR predicts superior survival in recurrent/metastatic HNSCC treated with cetuximab plus nivolumab
- Breg-related gene signature predicts survival and immune landscape in head and neck squamous cell carcinoma
- Regional motif diversity score in cfDNA predicts pembrolizumab response in head and neck cancer
- Phase 3 trial compares pembrolizumab with or without lenvatinib in PD-L1+ recurrent/metastatic HNSCC
- PD-1 inhibitors + chemo improve OS, PFS, ORR in first-line advanced ESCC; benefit limited in PD-L1 CPS <1