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N/A N=301 Randomized Treatment

Balloon Pump Assisted Coronary Intervention Study

Coronary Artery Disease · Left Ventricular Dysfunction

Enrolled (actual)
301
Serious AEs
0.7%
Results posted
Feb 2021
Primary outcome: Primary: Major Adverse Cardiac and Cerebrovascular Events — 23; 24 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Intra-Aortic Balloon Pump (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
British Cardiovascular Intervention Society
Primary completion
Jan 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Major Adverse Cardiac and Cerebrovascular Events
23; 24
SECONDARY
All-cause Mortality
SECONDARY
Major Procedural Complications
SECONDARY
Bleeding Complications (Major and Minor)
SECONDARY
Access Site Complications
SECONDARY
Transient Ischemic Attack
SECONDARY
Length of Hospital Stay
SECONDARY
Procedural Success

Summary

This study will test the hypothesis that elective use of the Intra-Aortic Balloon Pump (IABP) in patients undergoing high-risk Percutaneous Coronary Intervention (PCI) will reduce the rate of in-hospital major adverse cardiac and cerebrovascular events compared to patients who are managed without planned insertion of IABP.

Eligibility Criteria

Inclusion Criteria

  • impaired left ventricular function (Ejection Fraction < 30%)
  • large area of myocardium at risk (BCIS-1 Myocardial Jeopardy Score ≥ 8/12)

Exclusion Criteria

  • cardiogenic shock
  • acute STEMI within previous 48 hours
  • complications of recent AMI (including ventricular septal defect, severe mitral regurgitation, intractable ventricular arrhythmias)
  • contraindications to IABP use (including significant iliac or femoral arterial disease and more than mild aortic regurgitation)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00910481). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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