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Home › Conditions › left ventricular dysfunction

Left ventricular dysfunction

Part of Ventricular Dysfunction

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for left ventricular dysfunction

19 trials tracked for left ventricular dysfunction: 5 in phase 3 or 4 and 1 with published results. The most-cited published study has 75 citations.

19Trials tracked
5Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 5 Other / NA 9
  1. Phase 3 The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation Completed · 75 cited
  2. Phase 4 Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView. Completed
  3. Phase 4 Effects of Viagra on Heart Function in Patients With Heart Failure Completed
  4. Phase 4 Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone Completed
  5. Phase 3 The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction Completed
  6. Phase 2 Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) Completed
Show 13 more trials
  1. Phase 2 Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study) Completed
  2. Phase 2 Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study) Completed
  3. Phase 2 A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction Completed
  4. Phase 2 The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT) Completed
  5. N/A Phosphorous Magnetic Resonance Spectroscopy of Heart Completed
  6. N/A PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing Completed
  7. N/A A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System Completed
  8. N/A Strategic Management to Improve CRT Using Multi-Site Pacing Post Approval Study (Reference # C1918) Completed
  9. N/A IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting Completed
  10. N/A LifeVest Safety and Efficacy in Real Life Settings in France Completed
  11. N/A InterventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With LVAD's Completed
  12. N/A HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy Completed
  13. N/A Balloon Pump Assisted Coronary Intervention Study Completed

Showing the 19 most-cited and recently-updated of 19 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction
Cardiology RCT
Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction Heart Pump Strategy Backfires for Weakened Hearts During High-Risk Surgery
This randomized controlled trial enrolled 300 patients with severe left ventricular dysfunction and extensive coronary artery disease underg…
A heart pump meant to protect weakened hearts during surgery may increase death risk for patients with severe heart damage, new evidence sug…
May 7, 2026
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction
Cardiology RCT
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction New cell injections help heart patients feel better for six months
This phase I/IIb randomized controlled trial enrolled 31 treated and 12 control patients with recent large myocardial infarction and left ve…
Patients with recent heart attacks and weak heart pumps felt significantly better physically and socially after receiving new cell injection…
May 1, 2026

Research across Ventricular Dysfunction

Related studies from across the Ventricular Dysfunction family.

Statistical Analysis Plan Defines ICD Insertion Based on Ventricular Scar for Left Ventricular Systolic Dysfunction
Cardiology
Statistical Analysis Plan Defines ICD Insertion Based on Ventricular Scar for Left Ventricular Systolic Dysfunction New Heart Scan Strategy May Reduce Sudden Death Risk
This document is a statistical analysis plan outlining methods for a trial involving patients with mild moderate left ventricular systolic d…
A new trial plan tests if heart scans can better decide who needs a life-saving device to prevent sudden cardiac death.
medRxiv Apr 29, 2026
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF
Cardiology
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF Dapagliflozin linked to fat loss in heart failure patients
This preprint reports a non-randomized clinical trial in 60 patients with left ventricular diastolic dysfunction.
Adding dapagliflozin to standard care reduced epicardial fat in a small group of heart failure patients, though this preprint study needs co…
Apr 28, 2026
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts
Cardiology Cohort
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts Doctors Can Now Measure Your Heart’s True Age With One Scan
This cohort study involving 1,952 participants from the Project Baseline Health Study, 1,708 from WASE, and 313 from Stanford Cardiovascular…
A new scan tool calculates your heart's biological age to spot hidden risks before symptoms appear, though it is still experimental.
medRxiv Apr 19, 2026