N/A
Completed N=123
Intervention for Veterans With Depression, Substance Disorder, and Trauma
Depressive Symptoms · Substance-Related Disorders · Posttraumatic Stress Disorders
Source: ClinicalTrials.gov NCT00958217 ↗
Enrolled (actual)
123
Serious AEs
30.1%
Results posted
Mar 2016
Primary outcomePrimary: Depression Symptoms Were Assessed With the Hamilton Depression Rating Scale. — 31.92; 28.85 units on a scale — p=<.05
Summary
This study will compare two different types of psychotherapy for Veterans with depression, addiction, and a past traumatic experience. Everyone in the study will receive 12 weeks of group cognitive behavioral therapy focused on depression and addiction, followed by 12 weeks of individual psychotherapy sessions. For the second 12 weeks, half of the people will receive a review of the initial therapy, and half will receive a cognitive behavioral therapy focused on trauma. Everyone will complete research interviews every 3 months for a total of 18 months.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Depression Symptoms Were Assessed With the Hamilton Depression Rating Scale. |
31.92; 28.85 | <.05 sig |
| PRIMARY Posttraumatic Stress Disorder (PTSD) Symptoms |
58.4; 55.5 | <.05 sig |
| PRIMARY Timeline Followback |
.84; .81 | <.05 sig |
Eligibility Criteria
Inclusion Criteria
- Veterans 18 years of age and older living in the San Diego, California area
- Who are able to attend in-person therapy sessions
- Have depression, alcohol or substance addiction, and a past traumatic experience
Exclusion Criteria
- Non-veterans
- Individuals with schizophrenia or severe memory impairment
Data sourced from ClinicalTrials.gov (NCT00958217). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.