N/A Completed N=26 Other

Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity

Obesity · Vitamin D deficiency · Hypertension

Source: ClinicalTrials.gov NCT01068418 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2017

Primary outcomePrimary: The Change in the Mean Arterial Blood Pressure in Response to an Infusion of Angiotensin II — 1.97 mmHg — p=<0.05

Summary

Hypothesis: Vitamin D supplementation lower renin-angiotensin system activity in obesity. Specific Aim: To investigate whether Vitamin D supplementation in obesity improves the vascular sensitivity to angiotensin II.

Outcome Measures

Outcome	Result	p-value
PRIMARY The Change in the Mean Arterial Blood Pressure in Response to an Infusion of Angiotensin II	1.97	<0.05 sig
SECONDARY The Change in Renal Blood Flow in Response to an Infusion of Angiotensin II	-20.0	<0.01 sig

Eligibility Criteria

Inclusion Criteria

age 30 kg/m2,
stage I hypertension.

Exclusion Criteria

diabetes,
coronary heart disease,
heart failure,
renal failure,
liver failure,
hyperparathyroidism,
granulomatous disease.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01068418). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.