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N/A N=19 Randomized Double-blind Other

Maintaining Autonomy as we Age. Strategy Training for Age-related Executive Dysfunction.

Aging

Enrolled (actual)
19
Serious AEs
0.0%
Results posted
Jan 2017
Primary outcome: Primary: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM) — 50; 19.6; 50; 32.6 percentage of untrained goals improved — p=0.03

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Real world strategy approach (Behavioral); Psychosocial Education (Behavioral)
Age
Older Adult · 65+ yrs
Sex
All
Sponsor
Baycrest
Primary completion
Oct 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM)
50; 19.6; 50; 32.6; 36.4; 26.1 0.03 sig
SECONDARY
General Self Efficacy Scale (GSE)
29.10; 32.56; 30.90; 33.56; 30.50; 33.56 <0.05 sig
SECONDARY
Stanford Patient Education Research Center- General Health Subscale
2.20; 1.89; 2.20; 1.78; 2.20; 2.00 >0.05
SECONDARY
Stanford Patient Education Research Center- Health Distress Subscale
2.70; 4.22; 3.80; 3.67; 3.70; 4.11 >0.05
SECONDARY
Stanford Patient Education Research Center- Physical Activity Subscale
4.08; 5.31; 4.45; 3.64; 4.15; 3.19 <0.05 sig
SECONDARY
Stanford Patient Education Research Center- Communication With Physicians Subscale
8.40; 11.00; 9.50; 9.11; 10.00; 8.89 <0.1
SECONDARY
Stanford Patient Education Research Center- Visits to Physician and Emergency Department in the Past Six Months Subscale
2.30; 2.78; 1.50; 3.33; 2.00; 2.33 <0.05 sig
SECONDARY
Delis Kaplan Executive Function System (DKEFS) Tower Test- Mean First-Move Time
5.48; 6.13; 3.00; 3.69; 2.47; 1.72 <0.1
SECONDARY
DKEFS Tower Test- Achievement Score
17.10; 15.78; 18.30; 19.44; 20.90; 18.89 <0.05 sig
SECONDARY
DKEFS Word Fluency
55.30; 48.56; 56.40; 50.33; 57.40; 50.11 >0.05
SECONDARY
DKEFS Trail Making- Condition 4: Number-letter Switching
104.50; 91.11; 88.40; 80.56; 94.10; 84.44 >0.05

Summary

Healthy older adults with self-reported cognitive difficulties who receive strategy training will demonstrate greater performance benefits on measures of real-world activities, relative to those receiving a control intervention, immediately post treatment and at follow-up.

Eligibility Criteria

Inclusion Criteria

  • All participants must score within 1.5 standard deviation (SD) of age and education-corrected normative data for the Montreal Cognitive Assessment and on a battery of neuropsychological tests of attention, memory and executive function (which will insure that participants are unlikely to meet the criteria for Mild Cognitive Impairment (MCI)).
  • No clinically relevant depression (scores ≤22) on the Center for Epidemiologic Studies Depression Scale (CES-D)
  • Fluent in written and spoken English
  • Self-reported complains about cognitive function

Exclusion Criteria

  • Recent bereavement (within last 6 months)
  • History of neurological disease
  • Psychiatric illness requiring hospitalization and/or history or current substance abuse
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01163279). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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