Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging
Higher Alpha-Klotho Levels Mean Less Frailty And Better Bones
This systematic review and meta-analysis of 109 studies found that higher circulating α-Klotho levels were associated with lower odds of fra…
New research shows that higher Alpha-Klotho levels protect against frailty and bone loss, offering hope for better aging outcomes.
GWAS and Mendelian randomization link aging, rheumatoid arthritis, and herpes zoster via shared MHC signals
Shared genetic link found for aging, arthritis, and shingles
This genomic analysis integrates genome-wide association studies, multi-omics quantitative trait loci, linkage disequilibrium-aware colocali…
A shared genetic signal may explain why aging, rheumatoid arthritis, and shingles often overlap.
Narrative review discusses MEMR and MOCR recording techniques in aging adults with and without hearing loss.
Ear Reflexes Could Spot Hearing Loss Before It Starts
This review examines recording methods for middle ear muscle reflex and medial olivocochlear reflex across different age and hearing groups.…
New research on ear reflexes suggests they could reveal hidden hearing damage before standard hearing tests catch it.
Systematic review of antioxidant and anti-inflammatory strategies for male infertility and immune-mediated testicular disorders
Sperm Health Tied to Immune System in New Way
This systematic review synthesizes evidence on targeted antioxidant and anti-inflammatory interventions for male infertility and related imm…
John and Maria tried for years to have a baby.
Narrative review explores cytoskeleton-mediated autophagy regulation in neurodegeneration and aging
Review suggests cytoskeleton-autophagy axis may help treat neurodegeneration and aging
This narrative review examines the role of cytoskeleton-mediated autophagy regulation in the contexts of neurodegeneration and aging. The au…
Targeting the cell's structural framework and cleanup system could offer new ways to treat neurodegeneration and aging.
Resistance and interval training plus berry extract did not alter muscle AGEs in older adults
Exercise and berries did not change AGE levels in muscle tissue of older adults.
A 12-week RCT in 41 healthy adults aged 55-70 found that supervised resistance and high-intensity interval training, preceded by 30 days of …
Exercise and berry supplements did not lower advanced glycation end-products in the muscle tissue of healthy older adults in this study.
Systematic review examines nine therapeutic peptides for targeting aging hallmarks in older adults
Can peptides help us age better? A review looks at nine promising compounds.
A systematic review of 20 primary sources examined nine therapeutic peptides for healthy aging and age-related conditions in aging populatio…
Nine therapeutic peptides target aging biology, from restoring metabolism to protecting the brain, though experts warn more research is need…