N/A N=96 Randomized Treatment

Impact of Vitamin D Repletion in Hemodialysis Patients

Vitamin D Deficiency · End-stage Renal Disease

Bottom Line

View on ClinicalTrials.gov: NCT01175798 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Sep 2014

Primary outcome: Primary: Change in 25OH-Vitamin D Level — 15.8; 40.9 ng/dL

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Cholecalciferol (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Mehrotra, Anita, M.D.
Primary completion: Aug 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in 25OH-Vitamin D Level	15.8; 40.9	—
SECONDARY Change in Immune Parameters	—	—

Summary

Dialysis patients often suffer from defects in their immune system (that part of the body which fights infection). Evidence suggests that Vitamin D deficiency may have a negative effect on immunity, and many dialysis patients are deficient in Vitamin D. We believe that by giving Vitamin D to dialysis patients who are deficient, we may help improve their immune system. This study will test that idea.

Eligibility Criteria

Inclusion Criteria

Age > 18 years
Chronic hemodialysis treatments for at least 2 consecutive months
25OH-Vitamin D level < 25 ng/mL (inclusion criteria for randomization)

Exclusion Criteria

History of acute renal failure requiring dialysis with potential for renal recovery
History of HIV/AIDS
Inability to provide informed consent

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01175798). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.