N/A N=51 Randomized Triple-blind Prevention

IV Lidocaine on Postoperative Pain and QOR on Morbid Obese Patients Undergoing Bypass Surgery

Pain · Obesity

Bottom Line

View on ClinicalTrials.gov: NCT01180660 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2014

Primary outcome: Primary: Quality of Recovery 40 on the Day After Surgery — 165; 146 units on scale 40 (low) - 200 (high) — p=.01

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Lidocaine Infusion (Drug); Normal Saline (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Northwestern University
Primary completion: Oct 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Quality of Recovery 40 on the Day After Surgery	165; 146	.01 sig
SECONDARY 24 Hour Total Opioid Consumption	26; 36	—

Summary

Can Intraoperative systemic lidocaine decrease postoperative opioid consumption and improve quality of recovery after laparoscopic gastric bypass surgery? The hypotheses:does the use of intraoperative systemic lidocaine decrease postoperative opioid consumption and improve quality of recovery after laparoscopic gastric bypass surgery. This study has the potential to confirm an opioid sparing strategy for morbid obese patients undergoing laparoscopic gastric bypass surgery. The high incidence of obstructive sleep apnea and the increased risk of postoperative hypoxemia make the development of opioid sparing techniques in this patient population warranted.

Eligibility Criteria

Inclusion Criteria

ASA I, II,III;
BMI > 35 kg/m2,
Age between 18-70,
Fluent in English,
Patients undergoing laparoscopic gastric bypass,
EKG within 3 months.

Exclusion Criteria

History of allergy to local anesthetics,
History of chronic opioid use,
Pregnant patients,
History of EKG abnormalities.

Dropout: Conversion to open, patient or surgeon request.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01180660). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.