N/A
N=160
Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans
Distress · Anxiety · Depression · Postconcussive Symptoms
Bottom Line
View on ClinicalTrials.gov: NCT01253044 ↗Enrolled (actual)
160
Serious AEs
2.5%
Results posted
Oct 2015
Primary outcome: Primary: Brief Symptom Inventory 18 (BSI-18) — 73.3; 74.0; 65.0; 66.8 T-score — p=.912
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Acceptance and Commitment Therapy (Behavioral); Present Centered Therapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Veterans Medical Research Foundation
- Primary completion
- Aug 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Brief Symptom Inventory 18 (BSI-18) |
73.3; 74.0; 65.0; 66.8 | .912 |
| SECONDARY Sheehan Disability Inventory |
6.7; 6.4; 4.9; 5.3 | .273 |
Summary
This trial compares two psychotherapies, Acceptance and Commitment Therapy (ACT) and Present Centered Therapy (PCT), for veterans of the conflicts in Iraq and Afghanistan. We hypothesize that ACT will be more effective than PCT at reducing emotional distress and improving functioning. We further hypothesize that both interventions will be highly acceptable to participants.
Eligibility Criteria
Inclusion Criteria
- Previous deployment to OEF or OIF
- Current distress and impairment [at least one Diagnostic and Statistical Manual version IV (DSM-IV) anxiety or depressive disorder as determined by the Mini International Neuropsychiatric Interview (MINI) or post-concussive symptoms (PCS) as determined by a positive traumatic brain injury (TBI) screen with a score of 25 or greater on the Rivermead with distress or impairment related to PCS].
- Capable of giving informed consent.
Exclusion Criteria
- Cognitive impairment that would interfere with treatment. Potential participants will be excluded if they screen positive for more than mild cognitive impairment on the Montreal Cognitive Assessment (MoCA; excluded if score < 26).
- Severe psychopathology (psychosis, bipolar illness, urgent suicidality or self-injurious behavior) or untreated substance dependence in the past month.
- Anticipated change in pharmacologic intervention. Patients may stay on their current medications during the study but will be asked to refrain from beginning or altering medication use during the study to the extent possible.
- Other psychotherapy focusing on the same target symptoms. Patients may attend self-help groups or treatment for other types of problems (e.g., couples counseling) but not other treatment for the same presenting problems.
- Anticipated deployment or other circumstance that would interfere with completion of all study procedures.
Data sourced from ClinicalTrials.gov (NCT01253044). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.