N/A
Completed N=71
Long-term Caloric Restriction and Cellular Aging Markers
Source: ClinicalTrials.gov NCT01256840 ↗Enrolled (actual)
71
Serious AEs
0.0%
Results posted
Oct 2017
Primary outcomePrimary: Telomere Length — 0.96; 1.06; 1.06; 1.22 ratio
Summary
The purpose of this study is to see whether people who have restricted the number of calories they eat for a long period of time, compared to normal-eating and obese people, have markers of cellular aging that look younger.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Telomere Length |
0.96; 1.06; 1.06; 1.22; 1.20; 1.14 | — |
Eligibility Criteria
Inclusion Criteria
- Calorie restricting group: Self-reported caloric restriction for at least two years
- Calorie restriction group: BMI below 23
- Normal eating control: Normal eating (no history of caloric restriction) for two years
- Normal eating control: BMI below 30
- Obese comparison group: BMI above 30
- Obese comparison group: Normal eating (no history of caloric restriction) for two years
Exclusion Criteria
- Regular smoker for the past six months
Data sourced from ClinicalTrials.gov (NCT01256840). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.