N/A N=71

Long-term Caloric Restriction and Cellular Aging Markers

Aging

Bottom Line

View on ClinicalTrials.gov: NCT01256840 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2017

Primary outcome: Primary: Telomere Length — 0.96; 1.06; 1.06; 1.22 ratio

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of California, San Francisco
Primary completion: Aug 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Telomere Length	0.96; 1.06; 1.06; 1.22; 1.20; 1.14	—

Summary

The purpose of this study is to see whether people who have restricted the number of calories they eat for a long period of time, compared to normal-eating and obese people, have markers of cellular aging that look younger.

Eligibility Criteria

Inclusion Criteria

Calorie restricting group: Self-reported caloric restriction for at least two years
Calorie restriction group: BMI below 23
Normal eating control: Normal eating (no history of caloric restriction) for two years
Normal eating control: BMI below 30
Obese comparison group: BMI above 30
Obese comparison group: Normal eating (no history of caloric restriction) for two years

Exclusion Criteria

Regular smoker for the past six months

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01256840). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.