N/A
Completed N=8,202
HIV Cohort Study At Johns Hopkins University, University of North Carolina at Chapel Hill and Vanderbilt University
Source: ClinicalTrials.gov NCT01339416 ↗Enrolled (actual)
8,202
Serious AEs
—
Results posted
Apr 2014
Primary outcomePrimary: Incidence Rate of Malignancies — 0.30; 0.27; 0.02; 0.62 malignancies per 100 person-years
Summary
Human Immunodeficiency Virus (HIV) infected patients in the HIV registries of Johns Hopkins University, University of North Carolina and Vanderbilt University will be followed in the routine clinical care to estimate the rates of prespecified clinical events in this population.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Incidence Rate of Malignancies |
0.30; 0.27; 0.02; 0.62 | — |
| PRIMARY Incidence Rate of Acquired Immunodeficiency Syndrome (AIDS)-Defining Opportunistic Infections |
2.04; 1.72; 0.77; 0.66; 0.38; 0.37 | — |
| PRIMARY Incidence Rate of Myocardial Infarction |
0.27 | — |
| PRIMARY Incidence Rate of Liver Failure |
0.16 | — |
| PRIMARY Incidence Rate of Viral Encephalitis |
0.003 | — |
| SECONDARY Incidence Rate of Rhabdomyolysis |
0.10 | — |
| SECONDARY Incidence Rate of Death |
3.81 | — |
Eligibility Criteria
Inclusion Criteria
- HIV infection.
Exclusion Criteria
- None.
Data sourced from ClinicalTrials.gov (NCT01339416). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.