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Home › Conditions › AIDS

AIDS

Part of HIV-associated neurocognitive disorder

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for AIDS

38 trials tracked for AIDS: 7 in phase 3 or 4.

38Trials tracked
7Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 6 Phase 3 1 Phase 2 8 Phase 1 1 Other / NA 22
  1. Phase 4 Atripla to Stribild Switch Study to Evaluate Sleep Disturbances Completed
  2. Phase 4 SSRI Effects on Depression and Immunity in HIV/AIDS Completed
  3. Phase 4 Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care Completed
  4. Phase 4 Study To Investigate The Hemodynamic Effects Of Single Dose Vardenafil In Subjects Receiving Maraviroc Completed
  5. Phase 4 Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients Completed
  6. Phase 4 Cryptococcal Optimal ART Timing Trial Completed
Show 32 more trials
  1. Phase 3 Safety & Efficacy of Dual Therapy With Raltegravir/Lamivudine Completed
  2. Phase 2 Dose-ranging Study to Evaluate the Safety & Immunogenicity of a HIV Vaccine 732461 in Healthy HIV Seronegative Volunteers Completed
  3. Phase 2 Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients Completed
  4. Phase 2 A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma Completed
  5. Phase 2 Vitamin D Dose Finding Study Completed
  6. Phase 2 Evaluation of the Immune Response of a HIV Candidate Vaccine After Administration of One Chloroquine Dose Completed
  7. Phase 2 Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populations Completed
  8. Phase 2 Acute Effects of Cannabis on Cognition and Mobility in Older HIV-infected and HIV-Un-infected Women Completed
  9. Phase 2 Efficacy and Safety of GSK Biologicals HIV Vaccine in Antiretroviral Therapy (ART)-naïve HIV-1 Infected Persons Completed
  10. Phase 1 Effect of N-803 on B Cell Follicles in Antiretroviral Treated HIV Disease Completed
  11. N/A Personalized Text Messages to Improve Antiretroviral Treatment (ART) Adherence in HIV+ Methamphetamine Users Completed
  12. N/A The Effect of Protease Inhibitors on the Pharmacokinetics of Oral Norethindrone Contraception Completed
  13. N/A Perturbing of HIV Reservoir With Immune Stimulation Completed
  14. N/A Alcohol Pharmacotherapy for HIV+ Prisoners Completed
  15. N/A HIV HOspital TEsting: Bringing the Hidden to Light in the Hospital Setting Completed
  16. N/A Standardized Patients to Measure and Address Intersectional Stigma Completed
  17. N/A Pilot Study Evaluating the Use of Simultaneous HBV, HCV, and HIV Rapid Tests Completed
  18. N/A Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia Completed
  19. N/A Physiologic Growth Hormone Effects in HIV Lipodystrophy Completed
  20. N/A Pilot Project of Virologic and Immunologic Correlates of GALT Immune Reconstitution Following Raltegravir Therapy Completed
  21. N/A CSP #512 - Options in Management With Anti-Retrovirals Completed
  22. N/A HIV Cohort Study At Johns Hopkins University, University of North Carolina at Chapel Hill and Vanderbilt University Completed
  23. N/A HIV and Kidney Function Study Completed
  24. N/A Exercise and Pioglitazone for HIV-Metabolic Syndromes Completed
  25. N/A Kaiser Permanente HIV Cohort Study Completed
  26. N/A Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy Completed
  27. N/A Healing Hearts and Mending Minds in Older Adults Living With HIV Completed
  28. N/A Pilot Study of a Raltegravir Based NRTI Sparing Regimen Completed
  29. N/A Reducing Time to Spaced-out Appointments for Newly-diagnosed People Living With HIV Completed
  30. N/A Resistance Testing to Improve Management of Virologic Failure in Sub-Saharan Africa Completed
  31. N/A Care4Today v2.0 Application for Improving Adherence to HIV Medications Completed
  32. N/A Study to Optimize the Quality of Samples for Cell-mediated Immunity (CMI) in ART-naïve HIV-1-infected Subjects Completed

Showing the 38 most-cited and recently-updated of 38 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review finds intestinal microenvironment abnormalities are more severe in HIV immunological non-responders compared to responders
Allergy & Immunology Sys. Review
Systematic review finds intestinal microenvironment abnormalities are more severe in HIV immunological non-responders compared to responders HIV Treatment Leaves Some Patients Behind. Here's Why
This systematic review evaluated intestinal immune and microbial differences between people living with HIV (PLWH) classified as immunologic…
Some HIV patients stay vulnerable to illness even after years of successful treatment because their damaged gut fails to rebuild immunity.
Frontiers Apr 16, 2026
Nevirapine plus lamivudine and zidovudine improved lymphocyte counts and reduced adverse effects versus efavirenz in HIV patients
Infectious Disease RCT
Nevirapine plus lamivudine and zidovudine improved lymphocyte counts and reduced adverse effects versus efavirenz in HIV patients New HIV drug combo showed fewer side effects and better immune markers in small trial
This randomized controlled trial enrolled 100 patients with HIV/AIDS in a hospital setting.
A new HIV drug combo boosted immune cells and caused fewer side effects than the standard alternative in a recent trial.
NEJM Apr 14, 2026
HIV/AIDS continues disproportionate impact on U.S. Black or African American population
Allergy & Immunology
HIV/AIDS continues disproportionate impact on U.S. Black or African American population HIV and AIDS continue to disproportionately affect Black Americans, awareness day notes
A non-research announcement for National Black HIV/AIDS Awareness Day notes the continuing disproportionate impact of HIV infection and AIDS…
National Black HIV/AIDS Awareness Day highlights that HIV and AIDS continue to disproportionately affect Black or African American people in…
CDC Apr 4, 2026

Questions about AIDS

How does the impact of AIDS on Black Americans compare to other groups?

AIDS continues to impact Black Americans disproportionately compared to other groups in the United States, driven by structural factors and behavioral differences that persist despite similar risk behaviors.

Full answer →
How do intestinal immune differences compare between HIV responders and non-responders?

Intestinal immune problems are worse in HIV patients who do not recover their CD4 cell counts compared to those who do, showing more severe inflammation and bacterial imbalance.

Full answer →