N/A
Completed N=20
Glutathione and Health With Post-Polio Syndrome
Post-polio Syndrome · Physical Activity · Depression · Postoperative Pain
Source: ClinicalTrials.gov NCT01402570 ↗
Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Feb 2017
Primary outcomePrimary: PROMIS (Patient Reported Outcomes Measurement Information System) Physical Functioning — 37.8; 37.9; 37.5; 38.1 units on a scale — p=0.66
Summary
In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY PROMIS (Patient Reported Outcomes Measurement Information System) Physical Functioning |
37.8; 37.9; 37.5; 38.1 | 0.66 |
| PRIMARY Sleep Efficiency |
82.1; 86.9; 87.6; 87.8 | 0.44 |
| PRIMARY Steps Per Day |
4004.1; 3590.7; 3598.9; 3693.1 | 0.35 |
| PRIMARY PROMIS (Patient Reported Outcomes Measurement Information System) Fatigue |
56.0; 54.9; 53.4; 52.8 | 0.07 |
Eligibility Criteria
Inclusion Criteria
- Ability to walk 100 feet with usual assistive devices (ex. cane or walker)
- Having a function score of 18-32 when tested with the IPPS (Index of Post- Polio Sequelae). This will include people with post-polio symptoms in a very specific range of severity.
Exclusion Criteria
- Having another serious medical condition (cancer, multiple sclerosis, etc.)or inflammatory disease (ie., lupus)
- Currently taking glutathione or other antioxidants
Data sourced from ClinicalTrials.gov (NCT01402570). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.