N/A
N=40
Depression and ART Adherence in HIV+ Latinos
Depressive Symptoms · HIV Infections
Bottom Line
View on ClinicalTrials.gov: NCT01411839 ↗Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Mar 2018
Primary outcome: Primary: Depression From (1) Clinician-Administered MADRS Measure, and (2) Participant Self-Report Ratings With BDI-1a — 17.8; 19.2; 19.7; 17.7 Units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Cognitive-Behavioral Therapy (CBT-AD) (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Washington
- Primary completion
- Aug 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Depression From (1) Clinician-Administered MADRS Measure, and (2) Participant Self-Report Ratings With BDI-1a |
17.8; 19.2; 19.7; 17.7; 15.0; 11.8 | — |
| SECONDARY Self-Report Adherence |
92.6; 86; 93.5; 91.9 | — |
| SECONDARY MedSignals Electronic Pill-box for Adherence |
45.8; 28.8; 31.1; 20.0 | — |
Summary
The current HIV treatment adherence project was designed to adapt culturally and then pilot test an empirically supported cognitive-behavioral therapy program for adherence and symptoms of depression (CBT-AD)with HIV+ Latinos living on the U.S.-Mexico Border.
Eligibility Criteria
Inclusion Criteria
- HIV+ participants (a) currently receiving HIV care at La Fe CARE Center (study site);
- 18 years of age or older;
- Latino (i.e., self-identified as being of Mexican heritage);
- English- or Spanish-speaking
- capable of giving informed consent;
- currently on a prescribed antiretroviral regimen;
- suboptimally adherent (i.e., demonstrated either by a VL load taken in the last 12 months that is above the undetectable threshold of 50 mL copies or self-reporting a missed dose in the last two weeks);
- exhibiting some depressive symptomatology (i.e., scoring on the Beck Depression Inventory-1A 10 or above), and (i) male or female (including transgender Female-to-Male and Male-To-Female.
Exclusion Criteria
- actively psychotic or so cognitively impaired that they cannot participate,
- so physically ill as to be unable to come to the clinic to participate in the intervention, OR
- Report The use of crack, cocaine, heroin, OR methamphetamines to any extent in the past 40 days.
- Those who are planning on being away from the area for any extended period during the study (as in the case of seasonal workers) or whom
- have household members already enrolled in the study will also be excluded. We did choose to restrict study eligibility to individuals of Mexican descent.
Data sourced from ClinicalTrials.gov (NCT01411839). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.